多指标正交试验优化逍生散颗粒中白芍、五味子提取工艺  

Optimization of Extraction Process for Radix Paeoniae Alba and Schisandra Chinensis in Xiaosheng Pawder by Orthogonal Test with Multi-indexes

作　　者：张玲玲[1] 倪健[1] 张欣[1] 张娟[1] 王海涛[1] 付京[1] 张淼[1] 郝晓凤[2] 谢立科[2] 曲昌海[3] 

机构地区：[1]北京中医药大学中药学院,北京100102 [2]中国中医科学院眼科医院,北京100040 [3]北京中医药大学中药现代研究中心,北京100029

出　　处：《辽宁中医杂志》2016年第4期809-811,共3页Liaoning Journal of Traditional Chinese Medicine

基　　金：北京市科委科技计划"十病十药"专项(Z141100002214001)

摘　　要：目的:优选逍生散颗粒中白芍、五味子最佳提取工艺。方法:采用乙醇提取工艺,以白芍中芍药苷、五味子中五味子醇甲提取率以及浸膏得率作为评价指标,采用正交设计法考察乙醇浓度、溶剂用量、提取时间对提取结果的影响,最终确定最佳提取工艺。结果:白芍、五味子的最佳提取工艺为:采用10倍量60%乙醇,回流提取2次,每次2 h。结论:该提取工艺简便易行、稳定可靠,可为逍生散颗粒的工业化生产提供依据。Objective： To optimize the extraction process of Radix paeoniae alba and Schisandra chinensis in Xiaosheng Pawder. Methods： Orthogonal test design was used to study the influence of ethanol concentration,solvent volume,extraction time on extraction technology with the extraction rate of Radix paeoniae alba and Schisandra chinensis and extract yield as evaluation indexes to get the optimal extraction process. Results： The optimal extracting condition for the extraction was as follows： 10 folds of60% alcohol was used to extract 2 times,2 h for each time. Conclusion： The optimized extraction process,which was simple,stable and feasible,can provide the foundation for industrial production of Xiaosheng Pawder.

关 键 词：正交试验 白芍 五味子 逍生散颗粒 提取工艺 

分 类 号：R284.2[医药卫生—中药学]