3种中药成方制剂中何首乌、虎杖、决明子薄层鉴别方法的建立  

TLC identification of Polygoni Multiflori Radix, Polygoni cuspidati RhizomaEt Radix and Cassiae semen in Chinese patent medicines

作　　者：张丹丹[1] 徐新刚[2] 闫雪生[2] 

机构地区：[1]山东中医药大学,济南250355 [2]山东省中医药研究院,济南250014

出　　处：《中南药学》2015年第12期1310-1313,共4页Central South Pharmacy

摘　　要：目的建立中药成方制剂中含有何首乌、虎杖、决明子等药材的特异性成分的鉴别方法。方法采用薄层色谱法,何首乌以二苯乙烯苷、虎杖以虎杖苷、决明子以橙黄决明素为成分鉴别指标,对乙肝扶正胶囊、舒胆片、脂降宁片进行了药材鉴别研究,并与原方法进行了比较。结果新建立的薄层图谱成分斑点清晰,阴性样品无干扰。结论改进后的方法操作简单,结果稳定,特异性强,重复性好,可用于此3种中药成方制剂的质量控制。Objective To establish the thin layer chromatography（TLC） identification of the specificity ingredients Polygoni Multiflori Radix, Polygoni cuspidati Rhizoma Et Radix and Cassiae semen in traditional Chinese medicine preparations. Methods By TLC, 2, 3, 5, 4＇-tetrahydroxyl diphenylethylene-2-O-glucoside in Polygoni Multiflori Radix, polydatin of Polygoni cuspidati Rhizoma Et Radix and aurantio-obtusin in Cassiae semen were used as the detection index to determine the 3 herbs in Yigan Fuzheng capsules, Shudan tablets, and Zhijiangning tablets. Results Composition spots were clear without interference in the newly established TLC. Conclusion The improved method is simple, specific, and reproducible. It can be used in the the quality control of the 3 traditional Chinese preparations.

关 键 词：二苯乙烯苷 虎杖苷 橙黄决明素 蒽醌 薄层色谱 何首乌 虎杖 决明子 

分 类 号：R927[医药卫生—药学]