脾多肽注射液联合化疗治疗非霍奇金淋巴瘤的临床疗效观察  

Efficacy of lienal polypeptide injection combination chemotherapy in patients with non-Hodgkin′s lymphoma

作　　者：马艳苗[1] 杨欣欣[1] 袁叶[1] 彭涛 

机构地区：[1]山西中医学院,山西太原030024 [2]山西省中西医结合医院,山西太原030013

出　　处：《山西中医学院学报》2015年第6期51-53,共3页Journal of Shanxi College of Traditional Chinese Medicine

基　　金：山西省国际科技合作项目(2013081065-1);山西省回国留学人员科研资助项目(2014-088)

摘　　要：目的:观察脾多肽注射液联合化疗治疗非霍奇金淋巴瘤(NHL)的临床疗效及不良反应。方法:将98例NHL患者随机分为对照组(48例)和治疗组(50例)。对照组予单纯化疗(CHOP方案),治疗组给予化疗同期静脉滴入脾多肽注射液。结果:治疗组治疗后总有效率优于对照组(P<0.05);治疗后Karnofsky评分治疗组提高率为50%,对照组提高率为27%,两组比较差异有统计学意义(P<0.05)。结论:脾多肽注射液联合化疗治疗NHL能够提高总有效率,降低化疗的毒副作用,提高患者生存质量。Objective：To observe the curative effect and adverse reactions of lienal polypeptide injection combined with chemotherapy in treating non-Hodgkin＇s lymphomas（NHL）. Methods：98 patients with NHL were randomly divided into two groups. The patients in control group（48 cases）were treated with chemotherapy,the 50 patients in treatment group were treated with lienal polypeptide injection combined with chemotherapy. Results：The total efficiency rate of treatment group was higher than that of the control group（P〈0.05）. The improved rate of Karnofsky score was 50% in treatment group,and it was 27% in control group,there was significant difference between two groups（P〈0.05）. Conclusion：Compared with chemotherapy,lienal polypeptide injection combined with chemotherapy in treating NHL could increase total efficiency rate,and reduce the side effects,improve the survival quality of patients.

关 键 词：非霍奇金淋巴瘤 脾多肽注射液 化学疗法 临床观察 

分 类 号：R473.73[医药卫生—护理学]