120～430MeV/u碳离子的微剂量学特性研究（英文）  

Study on Microdosimetric Characteristics of 120 to 430 MeV/u Carbon Ion

作　　者：庞成果 苏有武[1] 徐俊奎[1,2] 李武元[1] 严维伟 姚泽恩[2] 

机构地区：[1]中国科学院近代物理研究所,兰州730000 [2]兰州大学核科学与技术学院,兰州730000

出　　处：《原子核物理评论》2015年第4期479-483,共5页Nuclear Physics Review

基　　金：National Major Scientific Instruments and Equipment Development Project(2011YQ12009610)~~

摘　　要：单粒子微剂量谱在放射治疗中是一个极其重要的参数,它可以用来评估辐射场的生物学效应。利用蒙特卡洛程序FLUKA模拟计算了由碳离子产生的混合辐射场能量沉积的微观模式。从已公开发表的文献中选取了实验测量300 MeV/u碳离子的线能能谱,并与相同物理条件下模拟计算得到的线能能谱相比较,结果吻合得很好。此外,还计算了120-430 MeV/u的碳离子的剂量平均线能能谱、频率平均线能和剂量平均线能。所得到的频率平均线能值为185-28.3 keV/μm而剂量平均线能值则为272-64.1 keV/μm。本文的结果对于制定碳离子放射治疗的治疗计划有着重要的意义。Microdosimetric single event spectrum is a signi？cant parameter in radiotherapy, which can be used to evaluate the radiation biological e？ect. In this paper, microscopic patterns of energy deposition are simulated with Monte Carlo code FLUKA at mixed radiation ？elds during carbon ions therapy. The results are compared with experimental measured results at 300 MeV/u carbon ion and good agreement has been found. Meanwhile, dose-weighted lineal energy spectra, frequency averaged lineal energy values and dose averaged lineal energy values of carbon ion with energy from 120 to 430 MeV/u were calculated,too. The frequency averaged lineal energy values are from 185 to 28.3 ke V/μm while the dose averaged lineal energy values are from 272 to 64.1 ke V/μm. These studies are useful for treatment plan in carbon ion radiotherapy.

关 键 词：微剂量 碳离子 蒙特卡洛 FLUKA 放射治疗 

分 类 号：O572[理学—粒子物理与原子核物理]