地佐辛防治全麻苏醒期躁动的效果分析  

The effect of Dezocine on the prevention of emergence agitation after general anesthesia

作　　者：黄敏坚[1] 卢炳益[1] 黄伟[1] 

机构地区：[1]百色市人民医院麻醉科,广西533000

出　　处：《中国临床新医学》2016年第4期326-329,共4页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

摘　　要：目的探讨地佐辛在防治全麻苏醒期躁动的临床效果。方法将2013-02-2014-12该院择期在气管插管全麻下进行手术治疗的94例患者按随机数字表法分为两组,观察组（48例）在手术结束前15 min静注地佐辛0.1 mg/kg,对照组（46例）在手术结束前15 min静注相同容积生理盐水,观察两组患者自主呼吸恢复时间、唤醒时间、拔管时间等,以及两组患者躁动发生率、不良反应发生情况。结果观察组躁动发生率和躁动程度明显低于和轻于对照组（P〈0.05）;观察组自主呼吸恢复时间和拔管时间比对照组明显缩短（P〈0.01）;观察组不良反应发生率低于对照组,但比较差异无统计学意义（P〉0.05）。结论地佐辛能有效预防全麻苏醒期躁动,并能缩短自主呼吸恢复时间和拔管时间。Objective To investigate the clinical effect of Dezocine on the prevention of emergence agitation（ EA） after general anesthesia. Methods Ninety-four patients undergoing elective surgeries under genetal anesthesia from February 2013 to December 2014 in our hospital were randonly divided into two groups. The observation group（ n = 48） was given dezozine（ 0. 1 mg/kg,i. v） at 15 minutes before the end of operation,and the control group（ n =46） was given the same volume of normal saline. The time points of spontaneous breathing recovery,eyes open,extubation and the incidence of EA and adverse reactions were compared between the two groups. Results The incidence of EA and the level of EA in the observation group were obviously lower or lighter that those in the control group（ P〈 0. 05）. The time of spontaneous breathing recover and extubation in the observation group was obviously shorter that that in the control group（ P〈 0. 01）. The rate of adverse reactions in the observation group was lower than that in the control group,but there was no signigicantly difference between the two groups（ P〈 0. 05）. Conclusion Dezozine can effectively prevent EA,and shorten the time of spontaneous breathing recovery and extubation.

关 键 词：地佐辛 全麻 苏醒期躁动 

分 类 号：R614.2[医药卫生—麻醉学]