尿崩症合并尿路扩张患者临床特点分析  

Clinical features of diabetes insipidus with urinary tract dilatation

作　　者：任柳[1] 吴红花[1] 张俊清[1] 高燕明[1] 郭晓蕙[1] 

机构地区：[1]北京大学第一医院内分泌科,100034

出　　处：《中华内分泌代谢杂志》2016年第4期312-314,共3页Chinese Journal of Endocrinology and Metabolism

摘　　要：尿崩症可导致尿路扩张，引起肾后性肾功能不全。本研究比较合并或不合并尿路扩张的尿崩症患者临床特点，结果显示合并尿路扩张者发病年龄更小，男性更多，病程更长，血肌酐水平更高，禁水加压素试验中尿渗透压及尿比重更低，其中病程为独立危险因素（OR=1．248）。肾性较中枢性、遗传性较获得性尿崩症发生尿路扩张的比例更高。Diabetes insipidus （DI） could lead to urinary tract dilatation, even renal dysfunction. This study compared clinical features of DI with or without urinary tract dilatation. The results showed that the former had earlier onset age, more male patients, longer duration, and higher serum creatinine, as well as lower urine osmotic pressure and urine specific gravity after injection of vasopressin. But only disease duration was the independent risk factor （ OR = 1. 248 ）. More nephrogenic DI and more hereditary DI were with urinary tract dilatation compared with central DI or acquired DI.

关 键 词：尿崩症 尿路扩张 肾功能不全 

分 类 号：R584.3[医药卫生—内分泌]