22906例孕妇乙型肝炎病毒感染状况的调查研究  

Analysis of clinical characteristics of 22906 gravidas with Hepatitis B Virus infection

作　　者：李飞凤[1] 袁国盛 周元平[2] 周洪波[3] 谭伟潮[3] 杨年欢[2] 刘俊维 黄华萍[2] 高云飞[1] 

机构地区：[1]南方医科大学南方医院妇产科,广州市510515 [2]南方医科大学南方医院感染内科,广州市510515 [3]南方医科大学南方医院病案科,广州市510515

出　　处：《实用医学杂志》2016年第8期1335-1338,共4页The Journal of Practical Medicine

基　　金：中国肝炎防治基金会课题(编号:XJS20120601)

摘　　要：目的:分析2008-2014年南方医院孕妇HBV感染情况。方法:回顾性分析这7年间于南方医院分娩的22 906例孕妇的资料。结果:孕妇的HBs Ag阳性率为9.45%,其中,广东籍、非广东籍的分别为11.64%、6.16%(χ2=193.370,P<0.005)。每年孕妇的HBs Ag阳性率分别为12.24%、12.98%、10.80%、9.36%、8.20%、8.03%、8.27%。HBe Ag阳性、HBe Ag阴性孕妇的ALT异常率分别为17.96%、6.68%(χ2=62.594,P<0.005);1992年前、后出生孕妇的HBs Ag阳性率分别为9.55%、6.64%(χ2=6.578,P=0.01)。结论:广东籍孕妇的HBV携带率高于非广东籍;孕妇HBs Ag阳性率呈逐年下降趋势;HBe Ag阳性孕妇中ALT异常率高于HBe Ag阴性孕妇;1992年后出生的孕妇,其HBV携带率明显下降。Objective To analyze the clinical characteristics of gravidas with HBV in Nanfang Hospital from 2008 to 2014.Methods 22 906 gravidas were retrospectively investigated.Results The HBs Ag positive rates were 11.64% and 6.16% when the gravidas were divided into Cantonese and non-Cantonese groups（χ2=193.370,P〈0.005）.The ALT abnormal rates in HBe Ag positive and HBe Ag negative gravidas were 17.96% and6.68%（χ2= 62.594,P〈0.005）.Conclusion The HBs Ag positive rate of gravidas in Guangdong and the ALT abnormal rate of HBe Ag positive gravidas are higher.

关 键 词：乙型肝炎 孕妇 阳性率 广东 

分 类 号：R714.251[医药卫生—妇产科学]