儿童铜绿假单胞菌感染的药物敏感性分析  

The Drug Sensitivity Analysis of Infection of Pseudomonas Aeruginosa in Children

作　　者：王秀明[1] 左新成[1] 张建军[1] 朱建平[1] 

机构地区：[1]潍坊市妇幼保健院,山东潍坊261011

出　　处：《中国医药指南》2016年第12期1-3,共3页Guide of China Medicine

基　　金：潍坊市卫生局2014年科研立项课题(编号2014025)

摘　　要：目的分析常用药物对儿童感染的铜绿假单胞菌的敏感性,为临床合理应用抗生素提供依据。方法用纸片扩散法对临床微生物实验室收集的366株铜绿假单胞菌进行药物敏感试验。结果药敏试验显示铜绿假单胞菌对哌拉西林、头孢哌酮/舒巴坦、头孢哌酮、头孢他啶、头孢吡肟、亚胺培南、阿米卡星、环丙沙星敏感性高,均>95%;头孢噻肟中介率高,达60.6%;对亚胺培南有一定的耐药率,为3.76%(12/319)。结论儿童分离出的铜绿假单胞菌对常用药物的敏感性明显高于成人,多重耐药现象少见。Objective To analyze the common drug sensitivity of Pseudomonas aeruginosa in children＇ infection. Method 366 strains Pseudomonas aeruginosa collected from clinical microbe laboratory were tested the drug sensitivity by disk diffusion method（K-B）. Result According to the susceptible test the drugs were sensitive（〉95%） as follows： piperacillin, cefoperazone/sulbactam, cefoperazone, ceftazidime, cefepime, imipenem, amikacim and ciprofloxacin. The intermediary rate of cefotaxime was higher（60.6%）. PA existed resisstant ratio（3.76%, 12/319） on impenem. Conclusion The drug sensitivity of Pseudomonas aeruginosa was higher in children than in adults and the incidence rate of muiti-drug resistance（MDR） was lower.

关 键 词：假单胞菌 铜绿 儿童 微生物敏感性试验 

分 类 号：R446.5[医药卫生—诊断学]