冻融周期中单个优质囊胚移植的应用  

The Application of Vitrified Single High-Quality Blastocyst Transfer

作　　者：廖宏庆[1,2] 周俊[3,2] 周静[2,4] 李梅清[2,4] 

机构地区：[1]南华大学附属第二医院泌尿外科,湖南衡阳421001 [2]南华星辉生殖健康专科医院 [3]南华大学附属第二医院检验科 [4]南华大学附属第二医院妇产科

出　　处：《中南医学科学杂志》2016年第2期195-197,208,共4页Medical Science Journal of Central South China

摘　　要：目的探讨冻融周期第5天单个优质囊胚复苏后移植的临床价值。方法回顾性分析2013年1月至2014年12月在我院接受首次复苏优质囊胚移植治疗的患者临床资料,按移植胚胎数分为单囊胚移植组(n=65)、双囊胚移植组(n=240),比较两组的妊娠率、种植率、多胎率、移植胚胎利用率。结果两组的临床妊娠率差异无统计学意义(P>0.05);单囊胚移植组种植率显著高于双囊胚移植组,差异有统计学意义(P<0.01);单囊胚移植组移植胚胎利用率显著高于双囊胚移植组,差异有统计学意义(P<0.05);单囊胚移植组多胎率显著低于双囊胚移植组,差异有统计学意义(P<0.01)。结论冻融周期行单个优质囊胚移植可以保证临床妊娠率,明显降低多胎率,提高胚胎利用率,获得较满意的临床结局。Objective To explore the clinical value of day 5 single high-quality frozen-thawed blastocyst transfer. Methods Retrospectively analyze patients＇ clinical documents on the first time treatment of high quality frozen-thawed blastocyst transfer in our hospital during Jan,2013 to Dec,2014.Compare the clinical pregnancy rate,implantation rate,multiple pregnancy rate and embryos utilization rate of the single blastocyst transfer group（ n = 65） and double blastocyst transfer group（ n = 240）,which were divided based on the number of embryos. Results There was no statistical difference between two groups on the clinical pregnancy rate（ P〈0.05）.but the implantation rate of single blastocyst group was higher than double blastocyst group（ P〈0.01）.The embryos utilization rate of single blastocyst group was higher than double blastocyst group（ P〈0.05）. The multiple pregnancy rate of single blastocyst group was lower than double blastocyst group（ P〈0.01）. Conclusion Single high-quality frozen-thawed blastocyst transfer can ensure clinical pregnancy rate,reduce multiple pregnancy rate and improve the embryos utilization rate.It achieved better clinical result.

关 键 词：冻融单囊胚移植 临床妊娠率 多胎率 胚胎利用率 

分 类 号：R711.6[医药卫生—妇产科学]