丹参酚酸类成分研究进展  

Research progress on salvianolic acids of Salvia miltiorrhiza

作　　者：梁文仪[1] 陈文静[1] 杨光辉[1] 朱丹[1] 毛鑫[1] 邵岩岩[1] 吴玲芳[1] 张晓雪[1] 张兰珍[1] 

机构地区：[1]北京中医药大学中药学院,北京100102

出　　处：《中国中药杂志》2016年第5期806-812,共7页China Journal of Chinese Materia Medica

基　　金：国家科技支撑计划项目(2012BAI29B01)

摘　　要：丹参药用历史悠久,资源丰富,为临床常用中药之一。现代研究表明酚酸类成分是丹参中的主要药效物质,具有保护心脑血管、抗肿瘤、抗氧化、抗炎、抗纤维化等作用,已被广泛应用于心脑血管等多种疾病治疗。该文对丹参酚酸类化学成分和近十年国内外药理研究进行全面总结,分析其研究和开发前景,以期为丹参酚酸类成分的深入研究和开发利用提供科学依据。Salvia miltiorrhiza is one of the most common traditional Chinese medicines. It has rich resources in China. According to modern studies,phenolic acids are the main effective components in S. miltiorrhiza. These components have cardiovascular and cerebrovascular protective effect,and anti-tumor,antioxidant,anti-inflammatory,and antifibrotic activities,etc. It has been widely used for the treatment of cardiovascular and cerebrovascular diseases and others. In this paper,the chemicals and pharmacological effects of phenolic acids from S. miltiorrhiza were summarized in the last decade. Its researches and development prospects were also analyzed for further studying and comprehensive utilization of these phenolic acids.

关 键 词：丹参 丹酚酸 心血管疾病 抗肿瘤 抗氧化 

分 类 号：R284.1[医药卫生—中药学]