血清光抑素C及β_2微球蛋白在妊娠期糖尿病患者肾功能评价中的临床意义  

Clinical significance of cystatin C and β_2-micoglobuimin in evaluation of renal function of gestational diabetes mellitus

作　　者：石祖亮[1] 王维鹏[1] 叶涛[2] 杨林[1] 洪媛[1] 王珍慧[1] 熊潜涛 

机构地区：[1]湖北省妇幼保健院检验科,武汉430070 [2]重庆市中山医院检验科,400013

出　　处：《中国优生与遗传杂志》2016年第4期72-73,共2页Chinese Journal of Birth Health & Heredity

摘　　要：目的探讨血清胱抑素C(Cys C)、β_2微球蛋白(β_2-MG)对妊娠糖尿病(GDM)患者肾损害的早期诊断价值。方法分别检测妊娠期糖尿病孕妇及健康对照组孕妇血清Cys C、β2-MG、尿素氮(BUN)、肌酐(Scr)、尿酸(UA)水平。结果 GDM组孕妇的Cys C、β_2-MG水平显著高于对照组(P<0.01),两组BUN Scr、UA比较无统计学意义。结论 Cys C、β_2-MG对更好的早期诊断GDM肾病具有重要意义。Objective：To study the early diagnosis value of serum cystatin C（Cys C）and β2-micoglobuimin（β2-MG）on renal injures of gestational diabetes mellitus（GDM）patients. Methods：The concentration of Cys C and β2-MG were determined by immune turbidimetric method. The levels of the blood urea nitrogen（BUN）,the creatinine（Scr）,and uric acid（UA）were measured by enzymatic method. Results：The levels of Cys C and β2-MG in patients with GDM were obviously higher than those of normal group（P〈0.01）. The level of BUN,Scr and UA had no significant difference in the two groups（P〈0.05）. Conclusion：The Cys C and β2-MG have important significance in the early diagnosis in patients with GDM.

关 键 词：血清光抑素C Β2微球蛋白 妊娠期糖尿病 

分 类 号：R714.256[医药卫生—妇产科学]