芪参益气滴丸治疗心肌桥伴心绞痛患者的有效性研究  

Efficacy study for Qishen Yiqi dropping pills in patients with myocardial bridge and angina pectoris

作　　者：张萍[1,2] 张广金 张虹[2] 

机构地区：[1]天津中医药大学,天津300193 [2]天津市南开医院心血管内科,天津300100 [3]天津市西青区中医院内科,天津300380

出　　处：《天津中医药》2016年第4期208-212,共5页Tianjin Journal of Traditional Chinese Medicine

基　　金：天津市卫生和计划生育委员会中医中西医结合科研课题(2015030)

摘　　要：[目的]观察常规西药联合芪参益气滴丸治疗孤立性心肌桥伴心绞痛(气虚血瘀型)的临床疗效。[方法]将60例孤立性心肌桥伴心绞痛(气虚血瘀型)患者随机分为两组,分别给予常规西药治疗(对照组)、西药联合芪参益气滴丸治疗(观察组)各30例。治疗8周后,比较两组心绞痛症状改善、西雅图心绞痛量表(SAQ)评分、气虚血瘀证积分和动态心电图结果。[结果]观察组心绞痛症状改善总有效率高于对照组,差异有统计学意义(P<0.05);观察组西雅图心绞痛量表评分升高,气虚血瘀证积分下降,与自身治疗前及对照组治疗后比较均有统计学差异(均达到P<0.05)。观察组动态心电图检查显示缺血型ST段变化的次数、最长持续时间、心肌缺血总负荷均下降,与自身治疗前及对照组治疗后比较均有统计学差异(均达到P<0.05)。[结论]芪参益气滴丸能提高孤立性心肌桥伴心绞痛(气虚血瘀型)患者的临床疗效。[Objective] To evaluate the efficacy of Qishen Yiqi dropping pills（QSYS） in the treatment of patients with isolate myocardial bridge and angina pectoris（Qi deficiency and blood stasis syndrom）. [Methods] The 60 patients with isolate myocardial bridge and angina pectoris（qi deficiency and blood stasis syndrom） were randomized into two groups,30 in the control group and 30 in the observed group.Both received conventional western medicinal treatment, with Qishen Yiqi dropping pills to the observed group additionally, for 8 weeks.The improvement of symptoms, the Seattle Angina Questionnaire（SAQ）, the scores of Qi deficiency and blood stasis syndrome and Holter examination results between two groups were compared. [Results] After 8 weeks of treatment, the total effective rates of symptomatic improvement in the observed group were significantly higher than that of control group（ P 0.05）.The SAQ in the observed group were significantly elevated, the scores of Qi deficiency and blood stasis syndrome in the observed group were significantly decreased comparison to before treatment and control group respectively（〈P0.05）.The Holter examination results, including frequency of ischemic ST segment variation, longest persistence time, overall load of myocardial isehemia in the observed group were significantly decreased comparison to before treatment and control group respectively（〈P0.05）. [Conclusion] Qishen Yiqi dropping pills could elevate clinical therapeutic effect in the patients with isolate myocardial bridge and angina pectoris（ Qi deficiency and blood stasis syndrom）.

关 键 词：芪参益气滴丸 心绞痛 孤立性心肌桥 

分 类 号：R541.4[医药卫生—心血管疾病]