清亮饮对兔玻璃体积血TNF-α表达影响的实验研究  

Experimental Study on the Effect of Qingliang Yin on the Expression of TNF-α in Rabbit Vitreous Hemorrhage

作　　者：回世洋[1] 张焱[2] 朱宁云[1] 

机构地区：[1]辽宁中医药大学附属医院,辽宁沈阳110032 [2]沈阳炮兵学院门诊部,辽宁沈阳110162

出　　处：《中医药学报》2016年第2期46-48,共3页Acta Chinese Medicine and Pharmacology

基　　金：沈阳市科技创新专项资金-应用基础研究专项项目(F13-316-1-50)

摘　　要：目的:探讨清亮饮治疗玻璃体积血的疗效。方法:40只日本大耳白兔随机抽取10只为空白对照组;其余30只确认玻璃体积血成功造模后再随机分成3组,分别为模型组中药(清亮饮)组和西药(安妥碘)组。各组干预8周后,收集玻璃体标本,检测TNF-α含量,观察眼底可见度的情况。结果:清亮饮组较模型组、安妥碘组中TNF-α含量降低。清亮饮组眼底可见度的恢复较模型组及安妥碘组快。结论:清亮饮对治疗兔玻璃体积血有显著疗效。Objective： To investigate the effect of Qingliang Yin in the treatment of vitreous hemorrhage. Methods： 40 Japanese white rabbits were randomly selected. 10 rabbits were in the blank control group; the remaining 30 rabbits with vitreous hemorrhage after successful modeling were randomly divided into 3 groups,the model group,Chinese medicine group（ Qingliang Yin） and the western medicine group（ Prolonium iodide）. Each group was inter vened for 8 weeks,and then vitreous body specimens wre collected to detect the content of TNF-α. Results： the content of TNF-α was reduced in the Qingliang Yin group compared with that in the model group and Prolonium iodide group. In the Qingliang Yin group the recovery of visibility of fundus was faster compared with that in the model group and the Prolonium iodide group. Conclusion： Qingliang Yin has a significantly curative effect on vitreous hemorrhage in rabbits.

关 键 词：清亮饮 玻璃体积血 兔 肿瘤坏死因子-Α 

分 类 号：R285.5[医药卫生—中药学]