双侧标准外伤大骨瓣减压术配合亚低温冬眠疗法救治急性外伤性脑肿胀  

Bilateral standard large trauma craniotomy combined with mild hypothermia hibernation therapy for acute traumatic brain swelling

作　　者：陈鸿尤 曹作为[1] 

机构地区：[1]海南省三亚市人民医院神经外科,海南三亚572000

出　　处：《河北医科大学学报》2016年第4期382-384,389,共4页Journal of Hebei Medical University

基　　金：三亚市医疗卫生科技创新项目(2014YW10)

摘　　要：目的探讨双侧标准外伤大骨瓣减压术配合亚低温冬眠疗法在急性外伤性脑肿胀治疗中的效果。方法选取急性外伤性脑肿胀患者112例,试验组68例应取双侧标准外伤大骨瓣减压术配合亚低温冬眠疗法,对照组44例应用常规去骨瓣减压术及常规治疗,观察并记录2组临床疗效。结果试验组临床疗效明显优于对照组,差异有统计学意义(Uc=3.839,P=0.001)。试验组治疗有效率(67.6%)明显高于对照组效率(27.3%),差异有统计学意义(P<0.01)。结论双侧标准外伤大骨瓣减压术配合亚低温冬眠疗法治疗急性外伤性脑肿胀效果显著,预后较常规治疗好。Objective To investigate the effect of bilateral standard large trauma craniotomy combined with mild hypothermia hibernation therapy in the treatment of acute traumatic brain swelling.Methods One hundred-twelve cases of patients with acute traumatic brain swelling were chosen to be observed and recorded the prognosis.Among them,68 cases as experimental group were took bilateral standard large trauma craniectomy coupled with mild hypothermia therapy,44 cases as control group were treated with conventional decompressive craniectomy and routine treatment.Results The clinical efficacy of the experimental group was significantly better than that of the control group,the difference was statistically significant（Uc=3.839,P=0.001）.The effective rate of the experimental group was（67.6%）,significantly higher than that of the control group（27.3%）,the difference was statistically significant（P〈0.01）.ConclusionThe effects of bilateral standard trauma large bone flap decompression combined with mild hypothermia hibernation therapy for acute traumatic brain swelling was significant,the prognosis is better than conventional treatment.

关 键 词：脑损伤 脑水肿 减压颅骨切除术 冬眠 

分 类 号：R651.15[医药卫生—外科学]