某院门诊药房2013年-2014年抗骨质疏松类药物利用分析  

Analysis of anti-osteoporosis drugs from 2013 to 2014 in the outpatient department of a hospital

作　　者：葛菁[1] 冯雷[1] 刘燕[1] 葛悦[1] 

机构地区：[1]中国医学科学院北京协和医院药剂科,北京100730

出　　处：《中国骨质疏松杂志》2016年第4期483-486,共4页Chinese Journal of Osteoporosis

摘　　要：目的分析我院西院区门诊药房抗骨质疏松类药物的使用情况及趋势,为临床合理用药提供参考。方法根据抗骨质疏松药的作用机制进行分类,采用WHO推荐的限定日剂量(DDD)频度分析法,对我院西院区门诊药房2013年1月-2014年12月抗骨质疏松药的销售金额、用药频度(DDDs)及日均费用(DDC)等进行回顾性分析。结果我院西院区门诊药房抗骨质疏松药销售金额呈增长趋势,2014年总销售金额比2013年增长了11.89%,降钙素类增长最为显著(增长率为43.36%),其次为双膦酸盐类(增长率为27.64%);碳酸钙片(协达利)连续两年DDDs居首位,DDC值最低(0.28)。我院多数抗骨质疏松药物的日均费用低于15元,协达利和阿法骨化醇软胶囊(阿法迪三)在同类药品中具有价格优势。结论钙制剂和活性维生素D两类药物在我院西院区门诊药房抗骨质疏松类药物的应用中占主导地位;双膦酸盐类和降钙素类分别在使用数量和销售金额具有显著增长趋势;抗骨质疏松药的药物经济学分析和用药趋势调查,对促进抗骨质疏松药的合理应用及临床用药监护具有重要意义。Objective To analyze the use of anti-osteoporosis drugs in the outpatient pharmacy of our hospital,and to provide reference for rational drugs use in clinic. Methods Anti-osteoporosis drugs were classified according to the mechanism. The sales of anti-osteoporosis drugs,defined daily dose（ DDD） frequency,and the average daily cost（ DDC） were retrospectively analyzed in the outpatient pharmacy of our hospital from January 2013 to December 2014,using the WHO-recommended DDD analysis method. Results The sale amount of anti-osteoporosis drugs showed a rising trend in the west zone outpatient of our hospital. The total sale amount increased by 11. 89% in 2014 comparing to that in 2013. The increase rate of calcitonin was the most significant（ 43. 36%）,the second one was bisphosphonates（ 27. 64%）. DDDs of calcium carbonate（ Xiedalli） stayed on the top in consecutive two years,and its DDC was the lowest（ 0. 28）. Most DDC of anti-osteoporosis drugs in our hospital was less than 15 Yuan. Xiedalli and alpha alfacalcidol soft capsules（ alfacalcidol） had price advantage among similar drugs. Conclusion Calcium products and active vitamin D stand dominant position among all anti-osteoporosis drugs in outpatient pharmacy of our hospital.Calcitonin and bisphosphonates showan increasing trend in both use quantity and sale amount. The economic analysis and trend investigation of anti-osteoporosis drugs have important significance in promoting the rational use of those drugs in clinic.

关 键 词：抗骨质疏松药 药物经济学 限定日剂量 门诊药房 药物利用 

分 类 号：R969[医药卫生—药理学]