原发性骨质疏松症的病因学研究进展  

Research progress in the etiology of primary osteoporosis

作　　者：秦集斌 宋洁富[1] 薛旭红[1] 

机构地区：[1]山西省人民医院骨科,太原030012

出　　处：《中国骨质疏松杂志》2016年第4期511-514,共4页Chinese Journal of Osteoporosis

摘　　要：原发性骨质疏松症包括绝经期后骨质疏松症与老年性骨质疏松症,此病严重后果会导致骨质疏松性骨折,患者遭受轻微创伤即可发生相应部位骨折,常见骨折部位包括脊椎、髋部、前臂,其中椎体、髋部骨折可显著增加患者病残率、致死率。女性人群中因骨质疏松导致骨折人数较患心脏病、中风、乳腺癌人数的总和还要多。骨质疏松症不仅影响患者身心健康、生活质量,还会导致巨额医疗消耗,因此逐步明确其病因显得尤为重要。国内外学者近年来研究发现,原发性骨质疏松症病因与内分泌因素、遗传因素、营养状况、物理因素、生活方式及心理状况等均有相关性。本文通过对相关文献的查阅,将原发性骨质疏松症病因学研究进展进行综述。Primary osteoporosis includes postmenopausal osteoporosis and senile osteoporosis. The disease can lead to severe osteoporotic fractures. Patients may have fractures in corresponding location after mild trauma. Common fracture sites include the spine,hip,and forearm. Among them,fractures in the spine and hip can significantly increase rates of disability and mortality. The number of women who have fracture due to osteoporosis is more than the sum of female patients with heart disease,stroke,and breast cancer. Osteoporosis not only affects the physical and mental health and quality of life,but also leads to huge medical consumption. Therefore it is important to gradually elucidate the cause of the disease. Scholars have found that the cause of primary osteoporosis is associated with endocrine factors,genetic factors,nutritional status,physical factors,way of life,and psychological status. In this paper,the research progress in the etiology of primary osteoporosis is summarized by relevant literature review.

关 键 词：原发性骨质疏松症 病因学 生活方式 

分 类 号：R681[医药卫生—骨科学]