颈动脉粥样硬化不同中医证型间合并靶器官损害情况比较  

The Comparative Observation on Target-organ Damages of Carotid Atherosclerosis with Different Chinese Medicine Syndrome

作　　者：杜文婷[1] 徐辉[1] 杜文娇[2] 陈明荃[1] 顾耘[1] 

机构地区：[1]上海中医药大学附属龙华医院,上海200032 [2]广东省深圳市宝安区中医院

出　　处：《中西医结合心脑血管病杂志》2016年第5期454-457,共4页Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease

基　　金：上海市科学技术委员会项目(No.14401972505);上海市卫生和计划生育委员会项目(No.2014LP089A)

摘　　要：目的比较颈动脉粥样硬化(CAS)病人不同中医证型合并靶器官损害的情况,探索中医对CAS规范化辨证论治的客观依据。方法通过临床流行病学调查方法,将511例颈动脉粥样硬化病人进行辨证分型,观察并比较各证型间病人合并靶器官损害情况。结果合并急性脑血管意外者,肾虚痰浊型最常见,其次为气虚痰浊型。合并肾功能不全者,肝肾阴虚型最常见,其次为肾虚血瘀型。合并外周血管病变者,肾虚痰浊型最常见,其次为肾虚血瘀型。合并周围神经病变者,肝肾阴虚型最常见,其次为肾虚痰浊型。合并眼底病变者,肾虚血瘀型最常见,其次为肾虚气滞型。结论各证型间合并急性脑血管意外、外周血管病变、周围神经病变、眼底病变、肾功能不全等疾病情况可以作为CAS辨证论证客观依据,为CAS选方用药提供一定依据。Objective To compare the rate of target-organ damages of carotid atherosclerosis（ CAS） with Chinese medicine syndrome differentiation,and to find the objective indicators for the standard traditional Chinese medicine（ TCM） syndrome differentiation of CAS. Methods Through document reference and expert consultation,syndrome differentiation of carotid atherosclerosis were diagnosed. By clinical epidemiological investigation,target-organ damages of 511 patients with CAS were observed and compared. Results Insufficiency of kidney essence and phlegm was the most common type in patients with acure cerebral vascular accident,while insufficiency of qi and phlegm type was the second. Insufficiency of liver yin and kidney yin was the most common type in patients with renal insufficiency,insufficiency of kidney essence and blood stasis type was the second. Insufficiency of kidney essence and phlegm was the most common type in patients with peripheral vascular disease,insufficiency of kidney essence and blood stasis type was the second. Insufficiency of liver yin and kidney yin was the most common type in patients with peripheral neuropathy,insufficiency of kidney essence and phlegm type was the second. Insufficiency of kidney essence and blood stasis was the most common type in patients with fundus lesions,insufficiency of kidney essence and qi stagnation type was the second（P〈0. 05）. Conclusion The complicated with acure cerebral vascular accident,renal insufficiency,peripheral vascular disease,peripheral neuropathy and fundus lesions can be used as an objective indicator of carotid atherosclerosis for TCM syndrome differentiation,so as to provide a certain basis for choosing therapy and herbs.

关 键 词：颈动脉粥样硬化 冠心病 中医证型 靶器官损害 

分 类 号：R259[医药卫生—中西医结合]