脂肪源性间充质干细胞在冠心病治疗中的研究进展  

Advances in the adipose-derived mesenchymal stem cells on the treatment of coronary heart disease

作　　者：郗锐 冯玙 李超敏[1] 武志芳[1] 

机构地区：[1]山西医科大学第一临床附属医院核医学科,太原030001

出　　处：《中华临床医师杂志（电子版）》2016年第8期131-134,共4页Chinese Journal of Clinicians(Electronic Edition)

摘　　要：间充质干细胞(MSC)也称为多能干细胞,是一种可自我复制,具有多向分化潜能的成体干细胞群。自体脂肪源性间充质干细胞(ADSC)来源充足,低免疫源性,经诱导后可向心肌细胞分化,在冠心病的研究中极具应用前景。查阅大量相关文献后,现就ADSC的生物学特性、细胞移植、体内示踪及冠心病治疗等方面的近期研究进展进行综合论述。Mesenchymal stem cells（MSC）, also known as multipotential stem cells, are a kind of adult stem cells which have self-replicating and multi-directional differentiation potential. Autologousadipose-derived mesenchymal stem cells（ADSC） can differentiate into the cardiomyocytes after induction. Besides, they have adequate sources and low immunogenicity. In short, ADSC possess a wide application prospect in the study of coronary heart disease. After reading lots of related literatures, recent research status about the ADSC from the following aspects in this paper was discussed, such as the biological characteristics of ADSC, cellular transplantation, tracing in the body, and the treatment of coronary heart disease.

关 键 词：间质干细胞 细胞移植 体内示踪 冠心病 

分 类 号：R541.4[医药卫生—心血管疾病]