中老年椎体骨赘和腰椎间盘退变的相关性  

Correlation of vertebral osteophyte and lumbar disc degeneration in the elderly people

作　　者：刘湘[1] 季伟[1] 李伦超 韦文武[1] 朱青安[1] 王吉兴[1] 

机构地区：[1]南方医科大学南方医院脊柱骨科,广州市510515 [2]解放军总医院第一附属医院,北京市100048

出　　处：《实用医学杂志》2016年第7期1133-1136,共4页The Journal of Practical Medicine

基　　金：广东省科技计划项目(编号:2014A020212723)

摘　　要：目的:分析中老年椎体骨赘与腰椎间盘退变的相关性及探讨骨赘形成的可能机制。方法:回顾性分析120例中老年腰腿痛患者,利用X线及MRI分别观察骨赘和腰椎间盘退变,根据Nathan方法将骨赘分为4度,定义Ⅱ度及以上为存在骨赘,再根据Pfirrmann方法将腰椎间盘退变分为5级,对所测参数进行统计学分析。结果:骨赘与年龄在各腰椎节段均呈正相关,相关系数r差异具有统计学意义(P<0.05);下腰椎L3/4、L4/5的骨赘比例(76.7%、70.8%)比上腰椎L1/2、L2/3(31.7%、46.7%)高,骨赘形成和腰椎间盘退变在各腰椎节段均呈正相关,相关系数r具有统计学差异(P<0.01)。结论:随着腰椎间盘退变加重,椎体骨赘形成越明显,腰椎间盘退变导致椎体应力过高是骨赘形成重要原因。Objective To analyze the correlation of vertebral osteophyte and lumbar disc degeneration in the elderly people and explore the possible mechanism of osteophyte formation. Methods X-ray and MRI data of 120 elderly people with backache or leg pain were retrospectively analyzed. Osteophyte was classified into four grades by X-ray according to the method proposed by Nathan. Discs with osteophyte were defined as occurring when osteophyte of grade II or greater were present. Lumbar disc degeneration was classified into five grades by MRI according to the method proposed by Pfirrmann. The obtained parameters were statistically treated and analyzed. Results Osteophyte and age were positively correlated at every lumbar disc level（P〈0.05）. The proportion of osteophyte in L3 / 4（76.7%） and L4 / 5（70.08%） were more severe than that in L1 / 2（31.7%）and L2 / 3（46.7%）. Osteophyte and lumbar disc degeneration were positively correlated at every lumbar disc level（P 〈0.01）. Conclusion Osteophyte becomes more severe with the increasing of lumbar disc degeneration.The vertebral stress after lumbar disc degeneration may be the main cause of osteophyte.

关 键 词：腰椎 骨赘 腰椎间盘 退变 相关性 

分 类 号：R681.53[医药卫生—骨科学]