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作 者:刘保萍[1] 王真[2] 毕学超 边焕茹[2] 崔松[2] 靳阳[3] 付静[1]
机构地区:[1]华北石油管理局总医院呼吸内科,河北任丘062552 [2]华北石油管理局总医院神经内科,河北任丘062552 [3]华北石油管理局总医院康复医学科,河北任丘062552
出 处:《中国医药导报》2016年第11期146-149,共4页China Medical Herald
基 金:华北油田公司科技项目(2015-HB-G11-03)
摘 要:目的探讨认知干预方案制订及实施对血管性轻中度认知功能障碍患者的影响。方法选取华北石油管理局总医院神经内科2015年3-10月收治的60例血管性轻中度认知功能障碍患者作为研究对象,依据随机数字表法分为对照组(30例)和观察组(30例),两组患者均使用养血清脑颗粒联合奥拉西坦胶囊治疗,维持血压、血糖水平稳定。对照组进行常规运动和认知康复训练,观察组给予多学科合作的专业化认知干预团队全程参与的认知干预方案,观察两组患者干预前后简易精神状态评价量表(MMSE)、蒙特利尔认知评估量表(Mo CA)、日常生活活动能力(ADL)评分。结果两组患者干预前MMSE、Mo CA、ADL评分比较,差异无统计学意义(P〉0.05)。观察组患者干预后MMSE、Mo CA、ADL评分均高于干预前和对照组,差异有统计学意义(P〈0.05)。结论认知干预方案制订及实施可显著改善血管性轻中度认知功能障碍患者的认知功能,早期干预治疗防止、推迟痴呆的进展,提高生活质量,改善疾病预后。Objective To study influence of cognitive intervention program formulation and implementation on patients with vascular mild-moderate cognitive dysfunction. Methods 60 patients with vascular mild-moderate cognitive dysfunction in Department of Neurology, Huabei Petroleum Administration Bureau General Hospital from March to October2015 were selected as study objects. The patients were divided into control group(30 cases) and observation group(30 cases) by using random number table method. Yangxue Qingnao Granules and Oxiracetam Capsules were used in two groups in order to cure and maintain blood pressure and blood sugar steadily. Regular sports and cognitive rehabilitation training were performed in control group. A cognitive intervention plan that participated by a multidisciplinary cooperation specialized cognitive intervention team entirely was provided to observation group. Mini-mental state examination(MMSE), montreal cognitive assessment(Mo CA), activity of daily living(ADL) scores before and after intervention between two groups were observed. Results There were no differences in MMSE, Mo CA, ADL scores of two groups before intervention(P〈0.05). After intervention, MMSE, Mo CA, ADL scores of observation group were higher than those before intervention and control group, with statistical differences(P〈0.05). Conclusion Formulation and implementation of cognitive intervention plan can improve the cognitive function of patients with vascular mild-moderate cognitive dysfunction, implement an early intervention treatment can prevent and postpone the progress of dementia, as well as enhance the standard of life and improve the prognosis of the disease.
关 键 词:血管性轻中度认知功能障碍 认知干预方案 日常生活活动能力
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