微创保胆取石术联合牛磺熊去氧胆酸与腹腔镜胆囊切除术治疗胆囊结石的疗效比较  

Comparison of curative effect of minimally invasive gallbladder preserving surgery combined tauroursodeoxycholic acid and laparoscopic cholecystectomy in the treatment of gallbladder gallstones

作　　者：郑邦瑞[1] 陈少逸[1] 黄辉宏 

机构地区：[1]汕头大学医学院第二附属医院普外科,广东汕头515041

出　　处：《临床普外科电子杂志》2016年第1期41-44,共4页Journal of General Surgery for Clinicians(Electronic Version)

摘　　要：目的探讨胆囊结石患者接受微创保胆取石术联合牛磺熊去氧胆酸与腹腔镜胆囊切除术治疗的效果对比。方法选择本院2013年2月至2014年7月收治的88例胆囊结石患者为研究对象,以随机数字表法分为A组44例,B组44例,A组接受微创保胆取石术联合牛磺熊去氧胆酸治疗,B组接受腹腔镜胆囊切除术治疗,对两组患者治疗后效果进行分析。结果 A组患者术后胆囊壁厚度与术前相比明显下降(P<0.05);A组术中出血量较B组低,术后恢复时间及住院时间明显较B组短,两组差异有统计学意义(P<0.05);A组术后1年腹泻、腹胀及右上腹不适等症状发生率明显低于B组,差异有统计学意义(P<0.05);结论胆囊结石接受微创保胆取石术联合牛磺熊去氧胆酸治疗可减少手术创伤,利于患者术后恢复,远期效果较好,值得推广。Objective To investigate the comparison of curative effect of minimally invasive gallbladder preserving surgery combined tauroursodeoxycholic acid and laparoscopic cholecystectomy in the treatment of the patients with gallbladder Gallstones. Methods 88 patients with gallbladder stone treated in our hospital from February 2013 to July 2014 were selected as the research object and were divided into group A （44 cases） and group B （44cases） with random number table method. Patients in group A treated with minimally invasive gallbladder preserving surgery combined tauroursodeoxycholic acid while patients in group B were treated with laparoscopic cholecystectomy. Effect analysis of the two groups was compared after treatment. Results The gallbladder wall thickness of the patients in group A after operation decreased significantly compared with that before operation （P〈0.05）. The blood loss during operation in group A was less than that in group B and postoperative recovery time and hospitalization time in group A were shorter than those in group B. The differences of the two groups had statistical significance （P〈0.05）. The incidence rates of diarrhea, abdominal distension and right upper abdominal discomfort and other symptoms in the patients of group A one year after operation were lower than those in group B and the differences were statistically significant（P〈0.05）. Conclusion Minimally invasive gallbladder preserving surgery combined tauroursodeoxycholic acid and laparoscopic cholecystectomy in the treatment of gallbladder Gallstones can reduce surgical trauma to patients, is good for postoperative recovery of patients and long-term effect is good, which is worthy of promotion.

关 键 词：牛磺熊去氧胆酸 微创保胆取石术 胆囊切除术 胆囊结石 

分 类 号：R657.4[医药卫生—外科学]