儿童肺炎支原体感染与血清维生素D水平的相关研究  

Relationship of the Mycoplasma Pneumonia Infection and Vitamin D levels in Children

作　　者：安娜[1] 刘运双[1] 陈曦[1] 高静[1] 

机构地区：[1]绵阳市中心医院检验科

出　　处：《现代检验医学杂志》2016年第2期117-119,共3页Journal of Modern Laboratory Medicine

摘　　要：目的探讨肺炎支原体（mycoplasma pneumonia，MP）感染与维生素D（Vitamin D，VitD）水平之间的相关性。方法以2014年7～10月间就诊的650例0～13岁人群为研究对象，采用被动凝集法检测其MP的感染情况，采用电化学发光法测定血清中VitD水平。结果研究对象的MP抗体阳性率为22．46％，MP抗体阳性组的VitD水平（中位数为28．06ng／ml，范围为8．99～64．84ng／ml）明显低于阴性组（中位数为32．48ng／ml，范围为8．54～67．31ng／ml），差异有统计学意义（u=-3．876，P=0．000）；VitD减低组的MP抗体阳性率（27．86％）明显高于VitD正常组（18．38％），差异有统计学意义（x2=8．222，P=0．004）；MP与VitD呈负相关（r=-0．180，P=0．000）。结论MP感染与VitD水平具有密切的相关性，MP感染可能导致VitD水平降低，VitD水平减低后也可能会导致MP感染。Objective To investigate the relationship between mycoplasma pneumonia （MP） infection and vitamin D（VitD） levels. Methods Subjects in the study were 650 children aged from 0 to 13 years old,passive agglutination method was used to measure the infection of mycoplasma pneumonia, and electrochemi｜uminescence assay was used to measure VitD in serum. Results MP antibody positive rate of the subjects in the study was 22.46 % ,the VitD levels of MP infected people （median = 28.06 ng/ml, 8.99 - 64.84 ng/ml） were significantly lower and the uninfected ones （median= 32.48 ng/ml, 8.54 - 67.31 ng/ml） ,and the difference was statistically significant（U=-3. 876, P= 0. 000）. MP antibody positive rate of VitD reduce group（28.06 % ） was significantly higher than that in normal VitD group （18.38 %）, and the difference was statistically significant （x2 =8. 222 ,P=0. 004）. VitD levels were negatively correlated with MP （r= -0. 180,P=0. 000）. Conclusion The MP infection was closely related to VitD levels, MP infection may lead to reduce VitD levels,and lower the VitD levels may also lead to MP infection.

关 键 词：儿童 肺炎支原体 维生素D 

分 类 号：R375.2[医药卫生—病原生物学] R446.112[医药卫生—基础医学]