H型高血压中医证型分布特点探析  

Study on Distribution of Traditional Chinese Mecial Syndromes in Patients with H-type Hypertension

作　　者：闫翠[1] 王琼[1] 杨忠奇[2] 冼绍祥[2] 

机构地区：[1]广州中医药大学岭南医学研究中心,广东广州510405 [2]广州中医药大学第一附属医院,广东广州510405

出　　处：《广州中医药大学学报》2016年第3期307-310,共4页Journal of Guangzhou University of Traditional Chinese Medicine

基　　金：广东省高水平大学建设基金资助项目(粤发[2015]3号)

摘　　要：【目的】探讨H型高血压中医证型分布特点。【方法】收集2014年6月至2015年1月中山大学附属第一医院收治住院的原发性高血压患者144例,通过检测其血浆同型半胱氨酸(Hcy)水平诊断H型高血压,对H型高血压患者进行中医辨证分型,统计分析比较各证型之间患者的性别、年龄、血压分级及Hcy水平。【结果】144例H型高血压患者可归属为痰湿壅盛证、阴阳两虚证、肝火亢盛证、阴虚阳亢证,其中痰湿壅盛证、阴阳两虚证分布最广。144例H型高血压患者男性所占百分比(106/144,73.6%)高于女性(38/144,26.4%);痰湿壅盛证H型高血压患者男性所占百分比显著高于肝火亢盛证、阴虚阳亢证,差异均有统计学意义(P<0.05)。痰湿壅盛证患者的Hcy水平最高(P<0.01),其他证型患者之间的Hcy水平差异无统计学意义(P>0.05)。3级H型高血压患者血浆Hcy水平高于1级和2级患者(P<0.05),1级和2级患者之间的Hcy水平差异无统计学意义(P>0.05)。【结论】H型高血压中痰湿壅盛证、阴阳两虚证分布最广,其中痰湿壅盛证患者的Hcy水平最高。Objective To investigate the distribution of traditional Chinese medical（TCM） syndromes of Htype hypertension. Methods A total of 144 essential H-type hypertension in-patients who were from the First Affiliated Hospital of Sun Yat-sen University admitted from June of 2014 to January of 2015 were enrolled into the study. The H-type hypertension patients were confirmed by detecting the plasma level of homosysteine（Hcy）,and then were differentiated into various TCM syndromes. The sex,age,blood pressure grading and plasma Hcy level of the patients with various syndromes were compared by statistical analysis. Results The 144 cases of H-type hypertension could be differentiated into internal abundant phlegm-damp syndrome, Yin and yang deficiency syndrome, liver- fire hyperactivity syndrome and yin deficiency with yang hyperactivity syndrome, and the first two syndromes had the highest percentages. Male occupied a higher percentage（106/144, 73.6%） than the female（38/144, 26.4%） in 144 cases, and the percentage of male in patients with internal abundant phlegm-damp syndrome was higher than that in patients with liver-fire hyperactivity syndrome and yin deficiency with yang hyperactivity syndrome,the difference being significant（P〈0.05）. The patients with internal abundant phlegm- damp syndrome had the highest plasma Hcy level（P0.01 compared with other syndromes）,and the differences between the left three syndromes were insignificant（P〉0.05）. Grade 3 H-type hypertension patients had higher plasma Hcy level than grade 1 and 2（P〈0.05）,but the difference of plasma Hcy level between grade 1 and 2 was insignificant（P〉0.05）. Conclusion H- type hypertension patients have dominant syndromes of internal abundant phlegm-damp syndrome and Yin and yang deficiency syndrome,and patients with internal abundant phlegm-damp syndrome have the highest level of plasma Hcy.

关 键 词：H型高血压 中医证型 痰湿壅盛证 阴阳两虚证 同型半胱氨酸 

分 类 号：R275.9[医药卫生—中西医结合]