多元福利措施改善巴马小型猪福利状况的实验评价  

Study on the Benefits of Multi-welfare Strategies in Minipigs

作　　者：胡樱[1] 杨斐[1] 

机构地区：[1]复旦大学实验动物科学部,上海200030

出　　处：《实验动物与比较医学》2016年第2期121-125,共5页Laboratory Animal and Comparative Medicine

基　　金：上海市科技发展基金项目（12140900900）

摘　　要：目的研究多元福利措施（组合应用音乐、香薰、营养、玩具、生物活性垫料等环境丰富元素1对实验小型猪整体福利状况的综合改善作用。方法将来自6窝的12头雌性巴马小型猪（每窝2头）分别编入常规饲养组和优化饲养组饲养9周，测定两组的应激分子表达、免疫平衡、血常规指标和生长情况。结果相比于常规饲养组，优化饲养组具有更低的皮质醇水平和干扰素-γ／白细胞介素．4比值，糖皮质激素受体（GR）mRNA和热休克蛋白70（HSP70）mRNA表达更少，红细胞数（RBC）、血红蛋白（HGB）、红细胞比容（HCT）、平均红细胞体积（MCV）、平均红细胞血红蛋白含量（MCH）、白细胞数（WBC）、中性粒细胞（NEUT）和嗜酸性粒细胞（EO）较高。结论采用多元福利措施的优化饲养有助降低日常饲养中小型猪的应激水平，提高抗应激能力，同时可引起免疫平衡和血常规指标相应改变。Objective To study improvements in well-being of minipigs with multi-welfare strategies （combine with music, aromatherapy oils, nutrients, toys, biological activity bedding）. Methods Twelve female Bama minipigs from 6 litters were used in this study, while every 2 pigs from the same litter were divided separately into conventional group and optimized group. After 9 weeks＇ rearing, the expression of stress-related molecules, immune balance, blood parameters and growth performance were measured. Results Pigs from optimized group display lower serum cortisol level and lower IFN-γ/IL-4 as well as lower expression in GR mRNA and HSP70 mRNA, meanwhile their RBC, HGB, HCT, MCV, MCH, WBC, NEUT and EO were observed higher than those from conventional group. Conclusion Multi- welfare strategies is benefit to reduce stress lever of minipigs and enhance their anti-stress ability, meanwhile, it can also change the immune balance and blood routine.

关 键 词：实验用小型猪 应激 环境丰富 

分 类 号：Q95-331[生物学—动物学]