三种处理产时宫颈水肿方法的效果比较  

Comparison of the effects of three different methods on cervical edema

作　　者：郑婕 何平 曾兰兰 

机构地区：[1]广州市妇女儿童医疗中心产科,广东省广州510623

出　　处：《中国基层医药》2016年第9期1288-1291,共4页Chinese Journal of Primary Medicine and Pharmacy

摘　　要：目的比较间苯三酚、宫颈注射或湿敷利多卡因三种方法在处理活跃期宫颈水肿中的作用。方法选取正常初产妇、宫口开大3~4cm伴宫颈水肿共262例,按数字表法随机分为A组89例、B组83例、C组90例。A组给予间苯三酚静脉注射,B组给予利多卡因宫颈注射,C组给予利多卡因湿敷宫颈。比较三组产妇用药后的宫颈变化、产程及母儿结局。结果A组、B组、C组用药后1h宫颈水肿消退率分别为79.8%、59.0%、57.8%,A组与B组、A组与C组间比较,差异均有统计学意义（χ2=4.31、5.04,均P〈0.05）,B组与C组间比较,差异无统计学意义（χ2=0.14,P〉0.05）。A组、B组、C组用药至宫口开全所需时间分别为（3.2±0.5）h、（4.1±0.6）h、（4.3±0.3）h,A组与B组、A组与C组间比较,差异均有统计学意义（t=0.91、1.06,均P〈0.05）,B组与C组间比较,差异无统计学意义（t=0.15,P〉0.05）;用药后2h宫颈水肿消退率（A组94.3%、B组95.2%、C组93.3%）、阴道分娩率（A组94.3%、B组91.6%、C组94.4%）、新生儿窒息情况（A组1例、B组0列、C组1例）和产后2h阴道出血量[A组（187±90）mL、B组（202±100）mL、C组（199±94）mL],三组间比较差异均无统计学意义（χ2=0.14、0.29、0.10,F=0.633,均P〉0.05）。结论间苯三酚静脉注射、利多卡因宫颈局部应用均有消除宫颈水肿的作用,其中以间苯三酚效果最佳,利多卡因的两种用法效果相当,三种治疗方法对母儿均无不良影响。Objective To compare the effect of phloroglucinol with lidocaine in treatment of cervical edemaat the active stage. Methods 262 normal primiparae with cervical edema were randomly divided into three groups.Group A（ 89 cases） was intravenously given phloroglucinol, group B（ 83 cases） was injected lidocaine into the cervix,group C（ 90 cases） was wet compress lidocaine on the cervix. The cervical change, progression of labor and maternaland fetal outcomes were compared among the three groups. Results The disappearance ratio of cervical edema after1h of group A, group B, group C were 79. 8%, 59. 0%, 57. 8% respectively, there were statistically significant differences between group A with group B and group C（ χ 2 =4. 31, 5. 04, all P 〈0. 05） , there was no statistically significantdifference between group B and group C（ χ 2 =0. 14, P 〉0. 05） . The mean time period from drug administration to fulldilation of the cervix of group A, group B, group C were （ 3. 2 ± 0. 5） h, （ 4. 1 ± 0. 6） h, （ 4. 3 ± 0. 3） h, there werestatistically significant differences between group A with group B and group C（ t = 0. 91, 1. 06, all P 〈 0. 05） , therewas no statistically significant difference between group B and group C（ t =0. 15, P 〉0. 05） . The disappearance ratioof cervical edema after 2h （ group A： 94. 3%, group B： 95. 2%, group C： 93. 3%） , vaginal delivery rate（ group A：94 3%, group B： 91. 6%, group C： 94. 4%） , asphyxia neonatorum（ group A： 1 case, group B： 0 case, group C： 1case） , and postpartum hemorrhage[ group A： （ 187 ±90） mL, group B： （ 202 ±100） mL, group C： （ 199 ±94） mL] hadno statistically significant differences among the three groups（ χ 2 = 0. 14, 0. 29, 0. 10, F = 0. 633, all P 〉 0. 05） .Conclusion Phloroglucinol and lidocaine all can treatment of cervical edema, the phloroglucinol is the best, two usesof lidocaine have same effect, there are no adverse effect on mother and newborn.

关 键 词：子宫颈 水肿 间苯三酚 利多卡因 

分 类 号：R714.4[医药卫生—妇产科学]