Therapeutic Effect of Chinese Herbal Ointment Liu-He-Dan in Patients with Acute Pancreatitis  

作　　者：Mei-Hua Wan Xian-Lin Zhao Wei-Wei Chen Juan Li Hui Guo Qing Xia Wen-Fu Tang 

机构地区：[1]Department of Integrated Traditional Chinese and Western Medicine, Sichuan Provincial Pancreatitis Center, West China Hospital, Sichuan University, Chengdu, Sichuan 610041, China

出　　处：《Chinese Medical Journal》2016年第9期1128-1130,共3页中华医学杂志（英文版）

基　　金：This work was supported by grants from the National Natural Science Foundation of China （No. 81374042 and No. 81370091）.

摘　　要：INTRODUCTION Severe acute pancreatitis （AP） remains a challenge in clinical practice, and there are no internationally agreed specific therapies. Severe AP typically presents with epigastric pain, abdominal distention, vomiting, and constipation at the early stage and is similar to the Yangming-Fushi syndrome of traditional Chinese medicine （TCM）. The Chinese herbal ointment Liu-He-Dan （LHD） has been adapted for the treatment of AP with Yangming-Fushi syndrome externally on belly for many years in our hospital. However, the potential mechanism of LHD in the treatment of severe AP has not been elucidated. Therefore, the present study sought to evaluate the effect of LHD on AP patients and preliminarily investigate its anti-inflammatory mechanism.INTRODUCTION Severe acute pancreatitis （AP） remains a challenge in clinical practice, and there are no internationally agreed specific therapies. Severe AP typically presents with epigastric pain, abdominal distention, vomiting, and constipation at the early stage and is similar to the Yangming-Fushi syndrome of traditional Chinese medicine （TCM）. The Chinese herbal ointment Liu-He-Dan （LHD） has been adapted for the treatment of AP with Yangming-Fushi syndrome externally on belly for many years in our hospital. However, the potential mechanism of LHD in the treatment of severe AP has not been elucidated. Therefore, the present study sought to evaluate the effect of LHD on AP patients and preliminarily investigate its anti-inflammatory mechanism.

关 键 词：Acute Pancreatitis Chinese Herbal Liu-He-Dan Proinflammatory Cytokines 

分 类 号：S858.28[农业科学—临床兽医学] TQ351[农业科学—兽医学]