养血清脑颗粒联合地巴唑治疗血管性头痛随机平行对照研究  

Yangxueqingnaokeli Joint Methimazole to Treat Vascular Headache Randomized Controlled Study

作　　者：陈湘勇 

机构地区：[1]湖南省冷水江展辉医院心血管内科,湖南娄底417500

出　　处：《实用中医内科杂志》2016年第4期68-70,共3页Journal of Practical Traditional Chinese Internal Medicine

摘　　要：[目的]观察养血清脑颗粒联合地巴唑治疗血管性头痛疗效。[方法]使用随机平行对照方法,将80例住院及门诊患者按抛硬币法简单随机分为两组。对照组40例尼莫地平,40mg/次,3次/d。治疗组40例养血清脑颗粒,4g/次,3次/d;地巴唑,20mg/次,3次/d。连续治疗28d为1疗程。观测临床症状、红细胞比容、纤维蛋白原、血浆黏度、全血比黏度、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈7例,显效15例,有效16例,无效2例,总有效率95.00%。对照组痊愈3例,显效9例,有效18例,无效10例,总有效率75.00%。治疗组疗效优于对照组(P<0.05)。血液流变学指标治疗组改善优于对照组(P<0.05)。[结论]养血清脑颗粒联合地巴唑治疗血管性头痛疗效满意,无严重不良反应,值得推广。[Objective] To observe the clinical efficacy of yangxueqingnaokeli joint methimazole to treat the vascular headache.[Methods] Randomly devided 80 patients into two groups.the control group of 40 patients used nimodipine, 40mg/time, 3 times/d. And the treatment group of 40 patients used yangxueqingnaokeli, 4g/time, 3 times/d; methimazole, 20mg/time, 3 times/d. 28 d of continuous treatment for a course.to observe the clinical symptoms, hematocrit, fibrinogen, plasma viscosity, whole blood viscosity and adverse reactions. One course of treatment determined the efficacy. [Results] The treatment group cured 7 cases, 15 cases markedly, effective in 16 cases, and invalid 2 cases,the total efficiency was 95.00%. The control group cured 3 cases,9 cases markedly, effective in 18 cases, and invalid 10 cases,the total efficiency was 75.00%. The efficacy of treatment group was better than control group（P〈0.05）. Blood rheology indexes improve treatment group is better than that of control group（P〈0.05）. [Conclusion] Yangxueqingnaokeli joint methimazole to treat vascular headache,the treatment effect was satisfied, had no serious adverse reactions,was worth for promotion.

关 键 词：血管性头痛 养血清脑颗粒 地巴唑 红细胞比容 纤维蛋白原 血浆黏度 全血比黏度 中西医结合治疗 随机平行对照研究 

分 类 号：R277.772[医药卫生—中医学]