疣状瓶霉所致着色芽生菌病一例  

Chromoblastomycosis caused by Phialophora verrucosa: a case report

作　　者：夏杨[1,2] 于长平[1] 王淑芬[1] 卢宪梅[1] 张艳芳[1] 孙勇虎[1] 刘红[1] 张福仁[1] 

机构地区：[1]山东省皮肤病性病防治研究所,济南250022 [2]济南大学山东省医学科学院医学与生命科学学院,济南250062

出　　处：《中国麻风皮肤病杂志》2016年第1期7-10,共4页China Journal of Leprosy and Skin Diseases

摘　　要：患者,男,60岁。右手腕红斑结痂,缓慢扩展16年。皮肤科检查：右手腕4 cm×6 cm环形暗红斑,皮疹边界清晰,覆有渗出性痂。真菌镜检见棕黄色圆形厚壁孢子。25℃沙氏葡萄糖琼脂培养基培养形成黑绿色绒毛状菌落,镜下见具领状结构的瓶形产孢细胞和花朵样排列的小分生孢子。PAS染色见厚壁孢子。诊断：疣状瓶霉引起的皮肤着色芽生菌病。治疗：给予伊曲康唑胶囊口服及盐酸特比萘芬乳膏外用,同时45~50℃热敷后治愈。A 60- years- old male patient presented with a 16- year history of progressively enlarging erythema and crusting on the right wrist. Physical examination revealed an annular erythema with clear boundary,exudative scab. The lesion was 4 cm × 6 cm in size. Many light brown akinetes were seen under microscopy. Olivaceous- black woolly bacterial colonies grew at 25℃ on Sabouraud＇s dextrose agar medium. Flask- shaped conidiogenous cells with collar structure and ellipsoidal conidia arranged in flower- like shape were seen under microscopically after cultured. PAS staining showed numerous akinetes. The diagnosis of chromoblastomycosis caused by Phialophora verrucosa was made. The patient was treated with oral itraconazole capsules,topical terbinafine hydrochloride cream and 45℃ ~ 50℃ hot compress. The lesion healed gradually.

关 键 词：着色芽生菌病 疣状瓶霉 

分 类 号：R756[医药卫生—皮肤病学与性病学]