纳洛酮治疗高血压性脑出血的疗效观察  

Observation on Efficacy of Naloxone in Treatment of Hypertensive Cerebral Hemorrhage

作　　者：许海兵[1] 

机构地区：[1]枝江市人民医院神经外科,湖北枝江443200

出　　处：《中国医院用药评价与分析》2016年第4期469-470,共2页Evaluation and Analysis of Drug-use in Hospitals of China

摘　　要：目的:探讨纳洛酮治疗高血压性脑出血的疗效。方法:选取枝江市人民医院2010年4月—2014年7月期间收治的154例高血压性脑出血的患者作为研究对象,按照随机数字表法分为观察组与对照组,每组各77例。2组患者选取不相同的措施治疗,观察并比较2组患者的疗效与并发症发生情况。结果:观察组患者的显效率为93.51%(72/77),有效率为80.52%(62/77),均明显高于对照组的81.82%(63/77)、50.65%(39/77),差异有统计学意义(P<0.05);观察组患者并发症发生率为10.39%(8/77),明显低于对照组的28.57%(22/77),差异有统计学意义(P<0.05)。结论:纳洛酮治疗高血压性脑出血效果较好,不良反应较少,值得临床推广。OBJECTIVE：To analyze and probe into the clinical application value of naloxone in treatment of hypertensive cerebral hemorrhage.METHODS：154 patients with hypertensive cerebral hemorrhage admitted into Zhijiang People＇s Hospital from April 2010 to July 2014 were selected to be divided into observation group and control group via the random number table,with 77 cases in each.Two group of patients were treated with different measures.The curative effects and complications of two groups were observed and compared.RESULTS：The significant efficiency and effective rate of observation group were respectively 93.51%（72 /77） and 80.52%（62 /77）,significantly higher than those of control group [81.82%（63 /77） and 50.65%（39 /77） ],with statistically significant difference（P〈 0.05）.Meanwhile,the incidence of complications in observation group was lower than that in control group[10.39%（8 /77） vs.28.57%（22 /77） ],and the difference was statistically significant（P 〈0.05）.CONCLUSIONS：Effect of naloxone in the treatment of hypertensive cerebral hemorrhage is better,less adverse reactions,worthy of clinical promotion.

关 键 词：脑出血 纳洛酮 高血压病 

分 类 号：R972.4[医药卫生—药品]