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作 者:杨少林[1] 张晓翠[2] 徐挺兰[1] 陈绪龙[1] 钟海利[3]
机构地区:[1]九江学院附属医院药学部,江西九江332000 [2]九江学院附属医院五官科,江西九江332000 [3]南昌大学第一附属医院药学部,江西南昌330000
出 处:《中国医院用药评价与分析》2016年第4期568-570,共3页Evaluation and Analysis of Drug-use in Hospitals of China
摘 要:目的:为重症医院获得性肺炎(hospital-acquired pneumonia,HAP)患者的合理用药提供参考。方法:分析1例重症HAP患者的抗菌药物、镇痛镇静药物的应用是否合理,监护药物之间相互作用及其不良反应。结果:依据美罗培南可以覆盖到重症HAP常见菌群,作为经验性治疗是合理的;患者有耐甲氧西林金黄色葡萄球菌感染,考虑年龄较大,给予替考拉宁抗感染是合理的;同时使用地佐辛止痛是合理的,但考虑各种止痛药的特性,该患者使用丙泊酚更佳;根据该患者使用的药物,应该监测患者的肝、肾功能,心律、血压、血脂和凝血功能;注意维生素C与其他药物之间的配伍。结论:结合患者各项指标和药物特性,选择最安全、最有效和最经济的治疗方案。OBJECTIVE:To provide reference of rational drug use for patient with severe hospital-acquired pneumonia(HAP).METHODS:The application rationality of antibiotics and sedation and analgesia drugs in onepatient with severe HAP were analyzed,the drug interactions and adverse drug reactions were monitored.RESULTS:Meropenem can cover severe HAP common flora,which can also be regarded as empirical treatment.It was rational to give teicoplanin to the elderly patient with MRSA infection;when combined with dezocine for analgesia,it was also rational,but considering the characteristics of various analgesics,propofol was the better one.According to drugs used by the patient,the liver and kidney function,heart rate,blood pressure,lipids and coagulation function of patients should be monitored.Compatibility between vitamin C and other drugs should be noticed.CONCLUSIONS:It is advisable to choose the safest,most effective and most economical treatment scheme with binding targets and medicinal properties for patients.
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