某院肿瘤患者使用升白细胞药的情况分析  

WBC Increasing Medicine Usage Analysis in Cancer Patients in a Hospital

作　　者：杨娜[1] 唐娜萍 龚建平[1] 李群[1] 肖坚[3] 

机构地区：[1]怀化市第二人民医院药剂科,湖南怀化418000 [2]怀化市第二人民医院肿瘤内二科 [3]中南大学湘雅医院药学部

出　　处：《中国药师》2016年第5期925-927,共3页China Pharmacist

基　　金：国家自然科学青年基金项目(81300204);长沙市科技计划重点项目(K1406004-31;K1308032-31)

摘　　要：目的：了解某院肿瘤患者升白细胞药的使用情况,规范该院肿瘤患者升白细胞药的使用。方法：采用回顾性分析方法,调查2014年1~12月某院诊断为恶性肿瘤并开具升白细胞药的患者病历579份,收集患者的基本信息、化疗情况、化疗后骨髓抑制情况和升白细胞药使用情况等信息,对升白细胞治疗的药物种类、给药时机、给药剂量、给药频次、使用疗程、联合用药以及溶媒的选择进行分析。结果：该院升白细胞药物以口服制剂为主;579例病例中合理用药病历414例,占71.50%,不合理用药病历165份,占28.50%,其中用药剂量和疗程基本符合要求,而不合理病例中主要以品种和给药时机不适宜为主,分别为42.42%和27.88%,其次为重复给药和联合用药不适宜,分别为13.33%和12.73,溶媒选择不适宜发生率较低,为3.64%。结论：该院肿瘤患者升白细胞药的使用有待规范,临床医师需加强升白细胞药应用知识的学习,合理使用该类药物。Objective：To investigate the application of leukogenic medicine in cancer patients and standardize the use of WBC increasing medicine in a hospital.Methods：A retrospective analysis of 579 patient records from January 2014 to December in a hospital diagnosed as malignant tumor and issued WBC increasing medicine.The kinds of drugs,timing of administration,dosage,frequency of administration,the use of medication,drug combination and the choice of solvent were analysed by collecting the patients＇ essential information,chemotherapy,myelosuppression etc.Results：The l white blood drugs mainly oral preparations;There were 414 rational drug use medication orders,accounting for 71.50 percent;irrational drug use medical record165,accounting for 28.50%.The dosage and duration of treatment in line with requirements,and unreasonable cases mainly suitable varieties and timing of administration based,42.42% and 27.88%,respectively;followed by repeated dosing and combination therapy is not suitable,13.33% 1and 2.73,respectively;a lower incidence of solvent choice unsuitable,is 3.64%.Conclusion：The use of WBC increasing medicine need to be standardized in cancer patients in the hospital.Clinicians need to strengthen studying the knowledge of the application of WBC increasing medicine and use WBC increasing medicine rationally.

关 键 词：肿瘤患者 升白细胞药 合理用药 

分 类 号：R97[医药卫生—药品]