红霉素及其衍生物促胃动力作用的文献计量分析  

Bibliometric Analysis of Erythromycin and Its Derivatives in Use of Promoting Gastric Motility

作　　者：王凯[1] 白艳[2] 梅和坤[1] 梁蓓蓓[1] 白楠[1] 李晨[1] 王瑾[1] 王睿[1] 

机构地区：[1]中国人民解放军总医院药物临床研究中心,北京100853 [2]中国人民解放军总医院临床药理研究室,北京100853

出　　处：《中国药物警戒》2016年第4期240-244,共5页Chinese Journal of Pharmacovigilance

基　　金："重大新药创制"科技重大专项个体化用药检测关键技术及相关产品研究课题(2012ZX09301003-005)

摘　　要：目的用文献计量学方法统计和分析国内外应用红霉素及其衍生物促胃动力作用的研究现状,扩大红霉素临床使用范围,合理用药。方法检索自中国知网(CNKI)建库以来到2015年8月,以及Embase,Pubmed,Web Of Science数据库中公开发表的文章,用End Note X7软件进行整理,对其发表年份、作者、文章类型、发表期刊进行计量分析。结果共纳入文献597篇。文献以临床研究和综述为主,其次为动物实验、病例分析、回顾性分析等。研究内容包括红霉素促胃动力作用的实验性研究、临床应用、不良反应、注意事项等。结论红霉素及其衍生物促胃动力作用治疗胃轻瘫,促进胃排空,尤其在治疗糖尿病胃轻瘫和新生儿喂养不耐受是目前研究的热点。Objective To use biblio metric analysis to do statistics and analyze domestic and international research status of erythromycin and its derivatives in use of promoting gastric motility, to expand the clinical use of erythromycin and assure rational drug use. Methods Embase,Pubmed,Web Of Science and CNKI were searched to collect all related literatures from beginning to August, 2015. Endnote X7 was used to sort out the type of literature, published year, fi rst author, research institution, published journal, cited frequency and research contents with bibliometric methods. Results 597 literatures were included. The literatures were mainly clinical researches and reviews, others include animal experiments, case reports, retrospective studies, etc. Research content includes experimental study, clinical application, adverse effect, and precautions of erythromycin and its derivatives in use of promoting gastric motility. Conclusion Erythromycin and its derivatives in use of promoting gastric motility, which is in treatment of gastroparesis, promoting gastric emptying, especially in diabetic gastroparesis and neonatal feeding intolerance, have become the research hotspot.

关 键 词：红霉素 胃动力 胃排空 胃轻瘫 

分 类 号：R969.3[医药卫生—药理学]