血液灌流联合血液透析治疗急诊重症有机磷农药中毒对疗效及预后的影响  

The curative effect of hemoperfusion combined with hemodialysis on acute organophosphorus pesticide poisoning

作　　者：刘鑫[1] 焦鹏[1] 井先成[1] 罗常月[1] 

机构地区：[1]商丘市第一人民医院急诊科,河南商丘476100

出　　处：《临床急诊杂志》2016年第4期283-285,共3页Journal of Clinical Emergency

摘　　要：目的:探究血液灌流(HP)联合血液透析(HD)治疗急诊重症有机磷农药中毒(AOPP)对疗效及预后的影响。方法:回顾性分析2013-01-2014-12我院诊治的110例AOPP患者临床资料,按照不同治疗方案分为2组,对照组(55例)予常规急救治疗,研究组(55例)采用HP联合HD治疗,对比2组临床治疗情况及预后。结果:研究组治疗总有效率92.73%显著高于对照组78.18%(P<0.05);昏迷清醒时间、胆碱酯酶(CHE)恢复时间等综合性指标均显著优于对照组(P<0.01,P<0.05);并发症总发生率显著低于对照组(P<0.05)。结论:AOPP患者接受HP联合HD治疗临床效果显著,同时可以降低并发症发生率,预后较佳。Objective：To explore the curative effect of hemoperfusion combined with hemodialysis on acute organophosphrous pesticide poisoning and its impact on the prognosis.Method：The clinical data of 110 patients with acute organophosphorus pesticide poisoning in our hospital between January 2013 and December 2014 were reviewed,and patients were divided into two groups（each with 55 cases）according to the different treatments.While the control group received routine treatment,the study group was treated with hemoperfusion combined with hemodialysis.The clinical effect and prognosis of the two groups were compared.Result：The total effective rate in the study group was 92.73%,significantly higher that（78.18%）in control group（P〈0.05）.The time for the recovery of consciousness and cholinesterase activity in the study group was significantly shorter than that in the control group（P〈0.01 or P〈0.05）.The overall incidence of adverse events was significantly lower in the study group than that in the control group（P〈0.05）.Conclusion：Hemoperfusion combined with hemodialysis is clinically effective in the treatment of severe acute organophosphorus pesticide poisoning,which can reduce the incidence of adverse events and bring about good prognosis.

关 键 词：血液灌流 血液透析 重症有机磷农药中毒 疗效 预后 

分 类 号：R595.4[医药卫生—内科学]