感染性休克患者预后与早期血乳酸清除率的关系  

Relationship between prognosis and early lactate clearance in patients with septic shock

作　　者：肖岳[1] 王洪桥[1] 赵同礼 牛柳卉 朱玉[1] 

机构地区：[1]界首市人民医院,界首236500

出　　处：《内科急危重症杂志》2016年第2期127-128,143,共3页Journal of Critical Care In Internal Medicine

摘　　要：目的:探讨感染性休克患者早期血乳酸清除率与预后的关系。方法:回顾性分析重症监护病房感染性休克患者56例的APACHEⅡ评分、入ICU 6 h后动脉血乳酸清除率及预后。分别将患者分成存活组(33例)和死亡组(23例),高乳酸清除率组(6 h乳酸清除率≥10%)和低乳酸清除率组(6 h乳酸清除率<10%),比较各组间的差异。结果:各组年龄、性别、APACHEⅡ评分和基础血乳酸值差异无统计学意义。存活组乳酸清除率明显高于死亡组[(29.8±15.0)%vs(9.7±8.6)%,P<0.05];高乳酸清除率组病死率均明显低于低乳酸清除率组(11.5%vs44.0%,P<0.01)。结论:早期乳酸清除率≥10%能准确评估感染性休克患者的预后。Objective： To explore the relationship between the early lactate clearance and prognosis in patients with septic shock. Methods： The APACHE Ⅱ score,arterial blood lactate clearance 6 hours after admission to intensive care unit and prognosis of 56 cases with septic shock were analyzed retrospectively. Patients were divide into death group（ 23 cases）and survival group（ 33 cases）,high lactate clearance group（ lactate clearance≥10% within 6 hours） and low lactate clearance group（ lactate clearance 10% within 6 hours）,and the differences were compared between the above groups. Results： There were no statistical significance in age,sex,APACHE Ⅱ score and the basic blood lactate value among these groups. The lactate clearance was obviously higher in survival group than that of death group [（ 29. 8 ± 15. 0） % vs（ 9. 7 ±8. 6） %,P 0. 05]. The mortality in high lactate clearance group was obviously lower than that of low lactate clearance group（ 11. 5% vs 44. 0%,P 0. 01）. Conclusion： The early lactate clearance 10% can accurately assess the prognosis of patients with septic shock.

关 键 词：感染性休克 乳酸清除率 重症监护 

分 类 号：R541.64[医药卫生—心血管疾病]