中国大陆首例输入性寨卡病毒病病例调查分析  

Survey of the first case of Zika virus disease in the mainland of China

作　　者：廖勇[1] 曾志笠 胡国良[3] 杨健平[1] 袁辉[3] 李建华[1] 张兴茂 黄仁发[1] 刘晓青[3] 

机构地区：[1]赣州市疾病预防控制中心传防科,341000 [2]南昌大学公共卫生学院流行病学教研室,330026 [3]江西省疾病预防控制中心应急传防所,南昌330029 [4]赣县疾病预防控制中心传防科,341100

出　　处：《中华流行病学杂志》2016年第5期593-596,共4页Chinese Journal of Epidemiology

摘　　要：目的分析2016年2月9日中国大陆首例确诊寨卡病毒病病例的流行病学特征，为防控寨卡病毒病提供参考依据。方法对中国大陆首例确诊寨卡病毒病病例进行流行病学调查并临床观察病例同行者与接触者。采集病例血清、尿液等标本，应用荧光定量RT-PCR进行核酸检测。结果该病例确诊为寨卡病毒病，于第18病日解除隔离、痊愈出院。病例第10病日血清标本和第11～13病日尿液标本检测均为寨卡病毒核酸阳性。该病例系江西省赣县籍外派工作回国人员，发病前在寨卡病毒流行地区有蚊虫叮咬史，同行者与接触者医学观察期内均未出现寨卡病毒病症状。结论该病例为中国大陆首例寨卡病毒感染确诊病例，系境外输入性病例，感染来源与在寨卡疫源地委内瑞拉蚊虫叮咬有关。Objective To analyze epidemiological characteristics of the first laboratory confirmed case of Zika virus disease in the China's Mainland, and provide evidence for the prevention and control of the spread of Zika virus disease. Methods Epidemiological survey was conducted for the first suspect case of Zika virus disease in China, and medical observation was conducted for the close contacts. The nucleic acid detection of Zika virus was conducted with Real-time RT-PCR by using blood and urine samples collected from the cases. Results The first case of Zika virus disease was confirmed. The case was cured and discharged on 18＇h day after the onset. The blood sample on 10~ day after the onset and urine samples on 11-13~ days after the onset were all positive for Zika virus. The case had the history of mosquito bites in the endemic country before the onset. The close contacts showed no Zika virus disease-like symptoms during the medical observation period. Conclusion The case reported by Jiangxi province was the first imported case of Zika virus disease in the mainland of China. The infection was related with the mosquito bites in Venezuela where Zika virus disease in endemic.

关 键 词：寨卡病毒 流行病学调查 

分 类 号：R512.8[医药卫生—内科学]