不同老年冠心病NYHA分级及分型患者血清感染性指标情况观察  

Study on serum infectious indexes in elderly patients with coronary heart diseases of different NYHA classes and types

作　　者：刘慕翔 禤志平 

机构地区：[1]广东省中山市古镇人民医院体检科,广东中山528421 [2]广东省中山市古镇人民医院感染科,广东中山528421

出　　处：《中国医药科学》2016年第8期77-79,共3页China Medicine And Pharmacy

摘　　要：目的观察不同老年冠心病NYHA分级及分型患者血清感染性指标情况。方法选取我院2011年10月~2014年10月期间接诊的78例老年冠心病患者作为研究对象,测量所有患者的IL-6、IFN-r、TNF-α、hs-CRP等感染性指标水平,对其结果进行比较分析。并比较所有患者中NYHA分级及分型患者血清感染性指标情况。结果在不同老年冠心病患者中,Ⅳ级患者IL-6、IFN-r、TNF-α、hs-CRP等感染性指标水平明显高于Ⅱ级、Ⅲ级患者,Ⅲ级患者的IL-6、IFN-r、TNF-α、hs-CRP等感染性指标水平明显高于Ⅱ级患者,差异有统计学意义（P〈0.05）。且不同老年冠心病分型患者中,心肌梗死型患者的IL-6、IFN-r、TNF-α、hs-CRP等感染性指标水平明显高于稳定性心绞痛、不稳定性心绞痛患者,而不稳定性心绞痛患者的IL-6、IFN-r、TNF-α、hs-CRP等感染性指标水平明显高于稳定性心绞痛患者,差异有统计学意义（P〈0.05）。结论老年冠心病患者的IL-6、IFN-r等血清感染性指标水平有明显升高的趋势,且不同的NYHA分级患者的血清感染性程度有明显的差异,在临床上具有较高的应用价值。Objective To explore the serum infectious indexes in elderly patients with coronary heart diseases of different NYHA classes and types. Methods 78 elderly patients with coronary heart diseases who were in our hospital from October 2011 to October 2014 were selected as research group, another 78 healthy aged person were selected as control group. The infectious indexes of IL-6, IFN-r, TNF-α, and hs-CRP in the two groups were tested and compared. The infectious indexes of patients with different NYHA classes and types in the research group were studied and compared. Results In the research group, the infectious indexes of IL-6, IFN-r, TNF-α, and hs-CRP were obviously higher than those of the control group, the differences were statistically significant（P〈0.05）, the infectious indexes of IL-6, IFN-r, TNF-α, and hs-CRP in patients with NYHA class Ⅳ were obviously higher than those of the patients with NYHA class Ⅱ and Ⅲ, while the indexes of patients with NYHA class Ⅲ were obviously higher than those of the patients with NYHA class Ⅱ, the differences were statistically significant（P〈0.05）, the infectious indexes of IL-6, IFN-r, TNF-α, and hs-CRP in patients with myocardial infarction were obviously higher than those of the patients with stable angina pectoris and unstable angina pectoris, while the indexes of the patients with unstable angina pectoris were obviously higher than those of the patients with stable angina pectoris, the differences were statistically significant（P〈0.05）. Conclusion The infectious indexes of IL-6, IFN-r, TNF-α, and hs-CRP in elderly patients with coronary heart diseases were obviously higher than those of healthy age person, and the indexes differ obviously in patients with different NYHA classes and types, which are therefore worthy of clinical promotion.

关 键 词：老年冠心病 NYHA分级 分型 血清感染性指标 

分 类 号：R541.4[医药卫生—心血管疾病]