肠道病毒71型感染致重症手足口病新认识  

Further recognition of severe hand, foot and mouth disease caused by Enterovirus 71

作　　者：邓慧玲[1] 张玉凤[1] 

机构地区：[1]西安市儿童医院感染二科,710003

出　　处：《中华实用儿科临床杂志》2016年第10期736-743,共8页Chinese Journal of Applied Clinical Pediatrics

基　　金：陕西省科学技术研究发展项目（2011K12-82）;陕西省统筹计划重点产业创新链项目（S2016TNSF0078）;西安市科学技术局医疗卫生研究项目（SF1208）

摘　　要：肠道病毒71型（EV71）感染致重症手足口病（HFMD）目前已成为威胁儿童身体健康和生命安全的主要疾病，是儿科医师和疾病预防控制系统，尤其是儿童重症医学专科医师均需要面对和解决的重要问题。迄今为止EV71感染致重症HFMD的致病机制仍未明确，其治疗方法临床存在诸多争议。因此，深入探讨EV71感染致重症HFMD的发生、发展机制，寻求新的有效防治途径，对于重症HFMD的早期识别、诊断和干预、降低患者的病死率及提高其生活质量具有重要意义。The severe hand,foot and mouth disease（HFMD） caused by Enterovirus 71 （EV71） has become a serious threat to children＇s health. It is an important issues which need to be faced and resolved by pediatrician and di- sease prevention and control system, especially pediatric critical care specialist. The pathogenesis of severe HFMD caused by EV71 has not been clearly defined so far, and the clinical treatment is controversial. So, to further explore the mechanism of EV71 infection in severe HFMD and explore new effective prevention and control methods, have important significance in reducing the mortality and improve the quality of life of patients with severe HFMD.

关 键 词：肠道病毒71型 重症手足口病 发病机制 临床表现 治疗 

分 类 号：R725.1[医药卫生—儿科]