联合疫苗接种免疫应答和安全性评估  

Immune response and safety evaluation of combined vaccination

作　　者：姚文清[1] 李艳伟[2] 王静艳[2] 

机构地区：[1]辽宁省疾病预防控制中心,辽宁沈阳110005 [2]中国医科大学附属盛京医院感染科,辽宁沈阳110022

出　　处：《中国实用儿科杂志》2016年第5期340-343,共4页Chinese Journal of Practical Pediatrics

摘　　要：联合疫苗是世界卫生组织(WHO)积极倡导的疫苗免疫发展方向,是减少接种次数、降低服务成本、减少预防接种异常反应、提高接种率的重要途径。重视联合疫苗在疫苗配伍和免疫应答、临床评价、安全性及有效性,对于推动联合疫苗在人群中逐步扩大应用,并适时纳入国家扩大免疫规划具有重要意义。Combination vaccines are the direction of develop- ment advocated actively by WHO, which is the way to minimize the number of injections children received, reduce the cost of service, mitigate abnormal reactions to inoculation and improve timely vaccination coverage. Paying attention to the combination vaccine from the aspects of vaccine formula, immunologic re- sponse, clinical evaluation, safety and effectiveness can promote the expanding application of combination vaccine gradually, and will be of great importance in bringing combination vaccine into Expanded Programme on Immunization.

关 键 词：联合疫苗 免疫应答 安全性 

分 类 号：R72[医药卫生—儿科]