58331例乙肝五项标志物定量检测不同模式分布分析  

Current mode distribution of the five Hepatitis B virus(HBV)markers for 58 331 cases

作　　者：吴著球[1] 张学东 

机构地区：[1]河南省南阳市第一人民医院输血科,河南南阳473000 [2]郑州安图生物工程股份有限公司,河南郑州450012

出　　处：《现代预防医学》2016年第9期1691-1694,共4页Modern Preventive Medicine

摘　　要：目的探讨南阳地区就医人群乙型肝炎病毒五项标志物模式的分布现状、特点及临床意义。方法收集2013年1月1日至2014年12月31日在我院住院或门诊检查乙型肝炎病毒五项指标定量检测的结果,进行不同模式归类分析。结果 58 331例乙型肝炎病毒五项指标定量检测结果出现22种模式,十分常见有两种,常见模式有三种,偶见模式有七种,罕见模式有五种,十分罕见模式有五种。男女不同模式构成比经统计学处理,P<0.01;其中模式3、4、5、7、9、10男女间比较,P<0.01,模式6、11男女间比较,P<0.05,其余模式男女间无统计学意义。结论(1)南阳地区就医人群对乙肝病毒的抵御能力较强,但乙肝五项全阴性模式比例较高,提示主动免疫工作有待加强。(2)男女分布有统计学差异的模式反映出女性感染乙肝病毒自我恢复能力较男性强,这也许是男性HBs Ag阳性模式占比高于女性的一个重要因素。Objective To investigate the current distribution, characterization and clinical value of the model of the five Hepatitis B virus （HBV） markers among people seeking medical advice in Nanyang zone. Methods The cases of the five HBV markers in the inpatient department or outpatient department of the first people＇s hospital of Nanyang during January 1, 2013 to December 31,201d were collected. The classified analysis was conducted using different models. Results There are 22 kinds of patterns among the results of 58331 cases to quantify the five HBV markers,including two extremely normal models, three normal models,seven occasional models,five rare models and five completely rare ones. The component ratio of five HBV markers models between male and female was significantly different at P 〈 0.01. However, the 3rd,4th,5th, 7th,gth and 10th models showed a significant difference between male and female at P 〈 0.01, and for the 6th and 11 th models were significant at P 〈 O. 05. Whereas, other models were non - significant in order to differentiate the component ratio of the HBV - markers between male and female. Conclusion （ 1 ） People seeking medical advice has powerful ability to resist HBV while the ratio of five HBV index with negative is slightly high. So active immunization work needs to be strengthened. （2） The models with the statistical difference between male and female demonstrate that women infected with the HBV have the greater self- recovering capacity than men. It may be the important factor why men have high positive HBsAg ratios than women.

关 键 词：乙型肝炎病毒 乙肝五项指标 定量检测 模式 

分 类 号：R115[医药卫生—公共卫生与预防医学]