广州市萝岗区C群流行性脑脊髓膜炎抗体水平调查分析  

Prevalence of antibody level against Neisseria meningitides serogroup C in luogang district,Guangzhou

作　　者：谢才文 唐薇 谭志勇 杜春生 田志鹏 张知光 

机构地区：[1]广州市萝岗区疾病预防控制中心,广东广州510530

出　　处：《现代预防医学》2016年第9期1702-1704,1708,共4页Modern Preventive Medicine

摘　　要：目的了解广州市萝岗区c群流行性脑脊髓膜炎抗体水平。方法2013年采取分层随机抽样的方法采集萝岗区8个不同龄组健康人群血清学进行抗体检测。结果萝岗区c群流行性脑脊髓膜炎血清杀菌抗体阳性率为60．30％（161／267），保护率为55．43％（148／267）。7～14岁最高，抗体阳性率和保护率高达94．59％和89．19％，其次是3～6岁，抗体阳性率和保护率均为75．32％，3岁以下儿童抗体阳性率和保护率最低，仅有26．23％和22．95％。结论萝岗区c群流行性脑脊髓膜炎抗体水平仍达不到防控要求；3岁以下散居儿童是c群流行性脑脊髓膜炎防控的重点人群。Objective To determine the antibody level against Neisseria meningitides serogroup C in Luogang district of Guangzhou. Methods Stratified randomized sampling method was adopted to collect blood specimens from the healthy people from 8 different age groups, in Luogang district of Guangzhou in 2013. The level of antibody against Neisseria meningitides serogroup C was measured and it＇s influencing factors was analyzed by multiple logistic regressions model. Results The overall positive and protective rate of serum antibody against group C was 60.30% （161/267） and （148/267） respectively. The highest positive and protective rate was 94.59% and 89.19% respectively in the 7 - 14 - year - olds,followed by the 3 - 6 - year-olds group （75. 32% ）. The lowest rate was 26. 23% and 22. 95% respectively in the 0 - 3 - year - olds group. Conclusion The level of antibody against Neisseria meningitides serogroup C is not enough to prevent meningococcal infection in the population. Meningococcal C vaccination and age were the influencing factors of protective antibody level. It is necessary to increase the level of protective antibody against serogroup C Neisseria meningitides in children under 3 years old.

关 键 词：流行性脑脊髓膜炎 C群 抗体水平 

分 类 号：R181.23[医药卫生—流行病学]