治疗幽门螺杆菌感染相关慢性胃炎的成本-效果分析  

Cost-effectiveness analysis of the therapeutic schemes for chronic gastritis affected by Helicobacter pylori

作　　者：张明[1] 倪颖[2] 陈相旭[1] 于波涛[1] 

机构地区：[1]原成都军区总医院药剂科,成都610083 [2]成都医学院第一附属医院药剂科,成都610513

出　　处：《药学服务与研究》2016年第2期126-129,共4页Pharmaceutical Care and Research

摘　　要：目的:探讨我国驻联合国黎巴嫩二级医院与黎巴嫩当地医院治疗幽门螺杆菌(Hp)感染相关慢性胃炎的经济效果。方法:回顾性分析152例确诊为Hp感染慢性胃炎病人,根据不同医院治疗方案将其分为A、B、C三组,A组(我国驻黎巴嫩二级医院)用药为:埃索美拉唑肠溶片+克拉霉素片+阿莫西林胶囊;B组(当地镇医院)用药为:奥美拉唑胶囊+阿莫西林胶囊+甲硝唑片;C组(当地诊所、药店)用药为:雷尼替丁胶囊+阿莫西林胶囊+硫糖铝片,疗程均为4周。分析三组病人治疗后的总有效率、Hp根除率、症状改善时间,并进行成本-效果分析。结果:A、B、C组总有效率分别为85.96%、78.85%、51.16%,成本-效果比分别为187.95、203.47、188.82。结论:A组治疗效果、成本-效果最优,其用药方案在治疗Hp感染相关慢性胃炎中具有最佳的性价比。Objective：To investigate the cost-effectiveness of therapeutic schemes in the treatment of chronic gastritis affected by Helicobacter pylori（Hp）in China peace-keeping hospital and Lebanon local hospitals.Methods：Totally 152 patients diagnosed as chronic gastritis which was affected by Hp were divided into 3groups.Group A（patients admitted into the China secondary hospital stationed in Lebanon）was treated with esomeprazole magnesium enteric-coated tablets,clarithromycin tablets and amoxycillin capsules.Group B（patients admitted into the local hospital）was treated with omeprazole capsules,amoxycillin capsules and metronidazole tablets.Group C（patients treated in the local clinic or the drug store）was treated with ranitidine capsules,amoxycillin capsules and ucralfate tablets.The treatment courses all lasted for 4 weeks.Total effective rate,Hp eradication rate and the time of symptom improvement of the 3groups were analysed and cost-effectiveness analysis was performed as well.Results：The total effective rates of the 3groups were 85.96%,78.85%and 51.16%,respectively.The cost-effectiveness ratio of the 3groups were 187.95,203.47 and 188.82,respectively.Conclusion：Group A was most superior in the therapeutic scheme among the 3groups and also had optimal cost-effectiveness ratio.

关 键 词：幽门螺杆菌 慢性胃炎 成本效果分析 药物经济学 维和行动 

分 类 号：R975.6[医药卫生—药品] R956[医药卫生—药学]