盐酸右美托咪定对连续硬膜外联合全麻下妇科腹腔镜手术患者全麻苏醒期的影响  

Effect of dexmedetomidine on recovery period of general anesthesia in patients with laparoscopic surgery by continuous epidural anesthesia combined with general anesthesia

作　　者：陶学有[1] 田华友 李晓明[1] 左美娟[1] 翟海霞[1] 

机构地区：[1]扬州大学医学院附属扬州市妇幼保健院麻醉科,江苏扬州225001

出　　处：《实用临床医药杂志》2016年第9期76-78,共3页Journal of Clinical Medicine in Practice

摘　　要：目的观察盐酸右美托咪定对硬膜外联合全麻下妇科手术患者全麻苏醒期的影响。方法 40例妇科手术患者随机分为盐酸右美托咪定组(D组)和丙泊酚组(P组)。记录实施麻醉前(T_1)、进入苏醒室时(T_2)、苏醒时(T_3)、拔除气管导管时(T_4)、离开苏醒室时(T_5)患者的HR、MAP和Sp O2值以及麻醉苏醒时间、拔除气管导管时间、术中知晓例数、恶心呕吐和寒战的发生例数。结果 2组T_1时间点各指标均无显著差异(P>0.05)。2组T_2、T_3、T_4和T_5时HR和MAP,苏醒时间、拔管时间、恶心呕吐和寒战的发生例数有显著差异(P<0.05)。结论盐酸右美托咪定应用于连续硬膜外联合全麻患者的全麻苏醒期血流动力学更加稳定,可以明显减少恶心呕吐等不适。Objective To explore the effect of dexmedetomidine（ DEX） on recovery period of general anesthesia in patients with laparoscopic surgery by continuous general epidural anesthesia combined with general anesthesia. Methods Forty patients were randomly divided into group D（ dexmedetomidine） and group P（ propofol）. The hemodynamic indexes such as HR,SpO2 and MAP were recorded at the time points of before anesthesia（ T1）,living in the recovery room（ T2）,analepsis（ T3）,extubation（ T4）,leaving the recovery room（ T5）,and the anesthesia recovery time,extubation time,intra-operative awareness,the cases of nausea and vomiting and chills were compared as well. Results There were no significant differences of indexes between two groups at T1（ P〉 0. 05）.There were significant differences in HR,MAP and incidences of anesthesia recovery time,extubation time,the cases of nausea and vomiting and chills at T2,T3,T4 and T5 between two groups（ P〈 0. 05）. Conclusion Application of dexmedetomidine in recovery period of general anesthesia in patients with laparoscopic surgery by continuous general epidural anesthesia combined with general anesthesia can maintain stability of hemodynamics and reduce the adverse reactions such as nausea and vomiting.

关 键 词：苏醒期 全麻 不良反应 右美托咪定 血流动力学 硬膜外阻滞 

分 类 号：R614[医药卫生—麻醉学]