快通道心脏麻醉用于心脏手术的临床观察  

Clinical Observation of Fast Channel of Cardiac Anesthesia for Cardiac Surgery

作　　者：宋磊军 魏金聚[1] 刘爱英[1] 

机构地区：[1]郑州市第七人民医院麻醉科,郑州450006

出　　处：《中国药房》2016年第14期1975-1978,共4页China Pharmacy

摘　　要：目的:观察快通道心脏麻醉用于心脏手术的临床效果与安全性。方法:134例心脏手术患者按随机数字表法分为对照组(66例)和观察组(68例)。对照组患者采用常规麻醉方法,观察组患者采用快通道心脏麻醉。比较两组患者的重症加强护理病房(ICU)住院时间、拔管时间、术后清醒时间、用药剂量、麻醉效果、治疗效果、血流动力学指标与术后感染情况。结果:观察组患者的ICU住院时间为(5.03±1.95)d,术后清醒时间为(35.31±11.30)min,气管拔管时间为(232.69±15.57)min,均明显短于对照组[分别为(10.03±2.35)d、(110.32±39.25)min、(345.56±43.28)min],差异均有统计学意义(P<0.05)。观察组患者使用舒芬太尼(653±148)μg、维库溴铵(0.30±0.02)mg/kg,用药剂量明显少于对照组[分别为(932±53)μg、(0.50±0.40)mg/kg],差异均有统计学意义(P<0.05)。观察组患者的镇痛效果明显优于对照组,且观察组患者的警觉/镇静评分(OAA/S)明显优于对照组,差异有统计学意义(P<0.05)。观察组患者的治愈率(88.2%)明显高于对照组(69.7%),肺部感染率(0)和支气管痉挛率(0)明显低于对照组(分别为6.1%、10.6%),差异均有统计学意义(P<0.05)。两组患者手术前、中、后各项血流动力学指标比较,差异均无统计学意义(P>0.05)。结论:快通道心脏麻醉在心脏手术中的效果良好、安全性高。OBJECTIVE：To observe the clinical efficacy and safety of fast channel of cardiac anesthesia for cardiac surgery.METHODS：134 cases of cardiac surgery were randomly divided into control group（66 cases）and observation group（68 cases）.Control group received routine anesthesia,and observation group received fast channel of cardiac anesthesia. The length of hospital stay in ICU,tracheal extubation time,postoperative waking hours,drug dosage,anesthetic effect,therapeutic efficacy,blood dynamics and postoperative infection were compared between 2 groups. RESULTS：The length of hospital stay in ICU,postoperative waking hours and tracheal extubation time of observation group were（5.03±1.95）d,（35.31±11.30）min and（232.69±15.57）min,which were significantly shorter than those of control group [（10.03 ± 2.35）d,（110.32 ± 39.25）min and（345.56 ± 43.28）min],with statistical significance（P〈0.05）. The dose of sufentanil and vecuronium bromide in observation group were（653 ±148）μg and（0.30±0.02）mg/kg,which were significantly lower than in control group [（932±53）μg,（0.50±0.40）mg/kg],with statistical significance（P〈0.05）. There was statistical significance in anesthetic effect between 2 groups,observation group was better than control group（P〈0.05）,and OAA/S of observation group were significantly better than that of control group,with statistical significance（P〈0.05）. The cure rate of observation group（88.2%） was significantly better than that of control group（69.7%）,and the rate of pulmonary infection（0）and bronchospasm rate（0）were significantly lower than those of control group（6.1%,10.6%）,with statistical significance（P〈0.05）. There was no statistical significance in blood dynamics between 2 groups（P〉0.05）. CONCLUSIONS：The effect of the fast channel of cardiac anesthesia is good and safety for cardiac surgery.

关 键 词：快通道心脏麻醉 心脏手术 临床效果 安全性 

分 类 号：R614.2[医药卫生—麻醉学]