老年慢性病患者肺部真菌感染的预防  

Prevention of pulmonary fungal infections in elderly patients with chronic diseases

作　　者：刘涓[1] 杨信才[1] 李小雷[2] 陈露[3] 石翠霞[1] 谢瑞娟[1] 高莉梅[4] 赵丹宁[4] 田红英[4] 李艳玲[5] 覃亮[1] 

机构地区：[1]河北大学附属医院康复医学科,河北保定071000 [2]河北大学附属医院感染控制办公室,河北保定071000 [3]河北大学附属医院呼吸科,河北保定071000 [4]河北大学附属医院护理部,河北保定071000 [5]河北大学附属医院结核科,河北保定071000

出　　处：《中华医院感染学杂志》2016年第9期1955-1957,共3页Chinese Journal of Nosocomiology

基　　金：河北省医学科技基金资助项目(201004023)

摘　　要：目的探讨老年慢性病患者继发性肺部真菌感染预防对策,为降低患者临床感染率提供依据。方法回顾性分析2013年9月-2014年12月医院收治的88例老年慢性病患者临床资料,将患者随机分为观察组和对照组,各44例;对照组给予常规护理和治疗,观察组患者在对照组基础上采取预防措施,对两组临床疗效进行对比分析;采用SPSS11.0软件进行统计分析。结果治疗7d后,观察组患者肺部真菌感染率为2.27%,对照组为29.55%,两组比较差异有统计学意义(P<0.05);治疗10d后,观察组临床治疗总有效率为97.73%,显著高于对照组的54.54%,两组比较差异有统计学意义(P<0.05);观察组有1例患者出现真菌耐药性,对照组有10例真菌耐药病例,两组比较差异有统计学意义(P<0.05);观察组患者住院时间和住院次数显著低于对照组患者,两组比较差异有统计学意义(P<0.05)。结论临床采取积极有效的预防措施可有效降低老年慢性病继发性肺部真菌感染率,减少患者住院时间和住院次数,提高临床疗效。OBJECTIVE To explore the prevention countermeasures for secondary pulmonary fungal infections in elderly patients with chronic diseases so as to reduce the clinical infection rate.METHODS The clinical data of 88 elderly patients with chronic diseases who were treated in the hospital from Sep 2013 to Dec 2014 were retrospectively analyzed,the patients were randomly divided into the observation group and the control group,with 44 cases in each.The control group was given the conventional nursing and treatment,while the observation group was treated with prevention measures based on the treatment of the control group.The clinical effects were observed and compared between the two groups,and the statistical analysis was performed with the use of SPSS11.0software.RESULTS The incidence rate of pulmonary fungal infections was 2.27%in the observation group after the treatment for 7days,29.55%in the control group,and there was significant difference between the two groups（P〈0.05）.The total effective rate of clinical treatment of the observation group was 97.73% after the treatment for 10 days,significantly higher than 54.54% of the control group,and there was significant difference between the two groups（P〈0.05）.After the treatment for 10 days,there was 1patient who showed fungal resistance in the observation group and 10 cases in the control group,with statistical significance（P〈0.05）.The length of hospital stay of the observation group was significantly shorter than that of the control group,the times of hospitalization of the observation group were significantly less than those of the control group,and there was significant difference between the two groups（P〈0.05）.CONCLUSIONIt is necessary for the hospital to take effective prevention measures so as to reduce the incidence of secondary pulmonary fungal infections in the elderly patients with chronic diseases,shorten the length of hospital stay,decrease the times of hospitalization,and improve the clinical effect.

关 键 词：老年慢性病 肺部感染 真菌 预防对策 

分 类 号：R379[医药卫生—病原生物学]