孕妇生殖道B族链球菌感染对妊娠结局的影响研究  

Influence of group B Streptococcusinfection in genital tract of pregnant women on pregnancy outcomes

作　　者：徐一鸣[1] 韩宁[1] 刘琰[1] 陈雁南[1] 王梦琦[1] 

机构地区：[1]郑州大学第三附属医院妇产科,河南郑州450052

出　　处：《中华医院感染学杂志》2016年第9期2128-2130,共3页Chinese Journal of Nosocomiology

基　　金：国家自然科学基金资助项目(30271358)

摘　　要：目的探讨妊娠36~38周孕妇发生B族链球菌（GBS）感染及对其妊娠结局的影响,为临床预防妊娠晚期孕妇发生GBS感染提供参考依据。方法选择2014年6月-2015年8月医院收治的36~38周孕妇336例为研究对象,所有孕妇在妊娠36~38周进行细菌培养,根据孕妇是否发生GBS感染分为观察组29例和对照组307例,比较两组孕妇妊娠结局;应用Stata12.0统计软件对数据进行统计分析。结果妊娠孕妇GBS感染率为8.63%;观察组宫内感染、胎膜早破、早产及产后出血的发生率分别为13.79%、17.24%、20.69%与13.79%均显著高于对照组的3.91%、2.61%、4.23%与2.28%（P〈0.05）;观察组新生儿黄疸、新生儿肺炎及新生儿窒息的发生率分别为20.69%、10.34%与13.79%均显著高于对照组的3.58%、0、1.63%,差异有统计学意义（P〈0.05）。结论孕妇生殖道发生GBS感染可导致宫内感染、胎膜早破、早产及产后出血的发生,增加新生儿黄疸、肺炎及窒息的发生,严重影响孕妇及新生儿的健康,临床应重视孕妇生殖道GBS感染的防治。OBJECTIVE To investigate the prevalence of group B Streptococcus（GBS）infection in the pregnant women with the gestational age varying from 36 and 38weeks and observe the influence on pregnancy outcomes so as to provide guidance for clinical prevention of GBS infection in the pregnancy women during late pregnancy.METHODS From Jun 2014 to Aug 2015,a total of 336 pregnant women with the gestational age varying from 36 and 38weeks were recuited as the study objects,then the bacterial culture was carried out for all the pregnant women from week 36 to week 38,the pregnant women were divided into the observation group with 29 cases and the control group with 307 cases according to the status of GBS infection,the pregnancy outcomes were compared between the two groups of pregnant women,and the statistical analysis of data was performed with the use of Stata12.0software.RESULTS The incidence rate of GBS infection was 8.63%in the pregnant women.The incidence rate of intrauterine infection of the observation group was 13.79%,significantly higher than 3.91% of the control group;the incidence rate of premature rupture of membrane of the observation group was 17.24%,significantly higher than 2.61% of the control group;the incidence rate of premature delivery of the observation group was20.69%,significantly higher than 4.23% of the control group;the incidence rate of postpartum hemorrhage of the observation group was 13.79%,significantly higher than 2.28% of the control group（P〈0.05）.The incidence rate of neonatal jaundice of the observation group was 20.69%,significantly higher than 3.58% of the control group;the incidence rate of neonatal pneumonia of the observation group was 10.34%,significantly higher than 0of the control group;the incidence rate of neonatal asphyxia of the observation group was 13.79%,significantly higher than 1.63% of the control group（P〈0.05）.CONCLUSION The genital tract GBS infection in the pregnant women may lead to the intrauterine infection,premature rupture of membranes,premature de

关 键 词：晚期妊娠 B族链球菌 妊娠结局 

分 类 号：R378.12[医药卫生—病原生物学]