电针与美洛昔康治疗早中期膝骨关节炎临床疗效比较:随机对照研究  

Clinical efficacy comparison between electroacupuncture and meloxicam in the treatment of knee osteoarthritis at the early and middle stage:a randomized controlled trial

作　　者：刚嘉鸿 宓轶群[1] 王华敏[1] 

机构地区：[1]上海交通大学附属第六人民医院针推伤科,上海200233

出　　处：《中国针灸》2016年第5期467-470,共4页Chinese Acupuncture & Moxibustion

基　　金：上海市卫生和计划生育委员会;上海市中医药发展办公室科研基金项目:ZY3-PCPY-3-1018;上海市卫生局中医药科研基金项目:2012J012A

摘　　要：目的:比较电针疗法与美洛昔康对早中期膝骨关节炎的临床疗效差异。方法:90例早中期膝骨关节炎患者随机分为电针组和美洛昔康组,每组45例。电针组电针犊鼻、内膝眼、梁丘、鹤顶、血海、阳陵泉、足三里,留针20min,每2d治疗1次;美洛昔康组口服美洛昔康片7.5mg,每日1次,两组均治疗6周。观察比较两组治疗前后西安大略麦克马斯特大学骨性关节炎指数(The Western Ontario and McMaster University Osteoarthritis Index,WOMAC)量表、股直肌肌张力测定、8英尺行走试验及5次坐立试验情况。结果:两组治疗后WOMAC量表各项积分均下降(均P<0.05),两组间比较差异无统计学意义(P>0.05);电针组治疗后股直肌肌张力较治疗前降低(P<0.05),电针组较美洛昔康组股直肌肌张力降低更明显(P<0.05);两组治疗后8英尺行走试验及5次坐立试验所用时间均缩短(均P<0.05),电针组较美洛昔康组缩短更明显(均P<0.05)。结论:电针与美洛昔康治疗早中期膝骨关节炎均有效,电针在改善股直肌肌张力状态、恢复膝关节内部力学平衡方面疗效优于口服美洛昔康。Objective To compare the clinical efficacy on knee osteoarthritis（KOA）at the early and middle stage between electroacupuncture（EA）and meloxicam.Methods Ninety patients of KOA at the early and middle stage were randomized into an EA group and a meloxicam group,45 cases in each one.In the EA group,EA was applied to Dubi（ST 35）,Neixiyan（EX-LE 4）,Liangqiu（ST 34）,Heding（EX-LE 2）,Xuehai（SP 10）,Yanglingquan（GB 34）and Zusanli（ST 36）;the needles were retained for 20 min and EA was applied once every two days.In the meloxicam group,the meloxicam tablets were prescribed for oral administration,7.5 mg,once a day.The treatment lasted for 6 weeks in the two groups.The Western Ontario and McMaster University Osteoarthritis Index（WOMAC）score,rectus femoris muscle tension,the 8-foot walking test and 5-time sit-to-stand test were adopted to observe and compare the effects in the two groups.Results After treatment,every item score in WOMAC was reduced after treatment（all P〈0.05）,but the difference was not significant between the two groups（all P〈0.05）.In the EA group,the rectus femoris tension after treatment was reduced as compared with that before treatment（P〈0.05）and the reducing result was much more apparent as compared with that in the meloxicam group（P〈0.05）.For the 8-foot walking test and 5-time sit-to-stand test,the time was shortened after treatment in the two groups（all P〈0.05）and the result in the EA group was much more obvious than that in the meloxicam group（both P〈0.05）.Conclusion Both EA and meloxicam are effective in the treatment of KOA at the early and middle stage.EA improves rectus femoris tension and recovers the internal mechanics balance and the efficacy is better than that of meloxicam.

关 键 词：膝关节 骨关节炎 电针 肌张力 随机对照试验 

分 类 号：R971.1[医药卫生—药品]