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机构地区:[1]广州中医药大学附属佛山市中医院内分泌糖尿病科,广东佛山528000 [2]广州中医药大学
出 处:《中国针灸》2016年第5期476-480,共5页Chinese Acupuncture & Moxibustion
摘 要:目的:比较针刺星状神经节配合静脉滴注前列地尔与单纯静脉滴注前列地尔治疗早期糖尿病下肢动脉粥样硬化的疗效差异。方法:将60例早期糖尿病下肢动脉粥样硬化患者随机分为观察组和对照组,每组30例。两组均予调控血糖、血脂等基础治疗,对照组采用前列地尔10μg加入0.9%NaCl溶液100mL静脉滴注;观察组在对照组治疗基础上加用针刺星状神经节治疗。两组均每日治疗1次,连续治疗2周为一疗程,共治疗4个疗程。观察两组患者治疗前后证候总积分、糖化血红蛋白(HbA1c)、胫后及足背动脉血流量,并比较两组临床疗效。结果:两组治疗后证候总积分、HbA1c、胫后及足背动脉血流量均较治疗前改善,治疗前后差异均具有统计学意义(均P<0.05),且观察组治疗后各项指标的改善均优于对照组,组间差异均具有统计学意义(均P<0.05);治疗后观察组总有效率为93.3%(28/30),优于对照组的86.7%(26/30,P<0.05)。结论:针刺星状神经节配合静脉滴注前列地尔治疗早期糖尿病下肢动脉粥样硬化疗效优于单纯静脉滴注前列地尔,可改善患者临床症状,调控血糖水平,增加下肢血流量。Objective To compare the efficacy between acupuncture at stellate ganglion combined with intravenous administration of alprostadil and simple intravenous administration of alprostadil on lower limb atherosclerosis of early diabetes mellitus.Methods Sixty patients of lower limb atherosclerosis of early diabetes mellitus were randomly divided into an observation group and a control group,30 cases in each one.Patients in the two groups were treated with basic treatment to control blood glucose and lipid.In addition,patients in the control group were treated with intravenous administration of alprostadil(10μg)and sodium chloride solution(100 mL);based on this,patients in the observation group were treated with acupuncture at stellate ganglion.The treatment was given once a day;the consecutive treatment of two weeks constituted one session,and totally 4 sessions were given.The total syndrome score,glycosylated hemoglobin(HbA1c),blood flow of posterior tibial artery and dorsal artery of foot were observed before and after treatment;the clinical efficacy was compared between the two groups.Results Compared before treatment,the total syndrome score,HbA1 c,blood flow of posterior tibial artery and dorsal artery of foot were significantly improved after treatment(all P〈0.05),which were more obvious in the observation group(all P〈0.05).After treatment,the total effective rate was 93.3%(28/30)in the observation group,which was significantly superior to 86.7%(26/30)in the control group(P〈0.05).Conclusion Acupuncture at stellate ganglion combined with intravenous administration of alprostadil achieve better effect than simple intravenous administration of alprostadil for lower limb atherosclerosis of early diabetes mellitus,which improve the clinical symptoms,regulate blood sugar and increase the blood flow of lower limb.
分 类 号:R246.1[医药卫生—针灸推拿学]
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