中药调周法对卵巢储备功能下降患者性激素和卵巢动脉血流的影响  

Impact of herbal menstruation-regulating therapy on sex hormones and ovarian artery blood flow in patients with diminished ovarian reserve

作　　者：应敏丽[1] 徐旭群[1] 王佳曦[1] 

机构地区：[1]浙江中医药大学第一临床医学院妇科,浙江杭州310006

出　　处：《上海中医药杂志》2016年第5期58-60,共3页Shanghai Journal of Traditional Chinese Medicine

摘　　要：目的探讨中药调周法对卵巢储备功能下降(DOR)患者性激素水平及卵巢动脉血流的影响。方法将74例DOR患者随机分为治疗组和对照组,各37例;对照组口服克龄蒙片,治疗组在对照组基础上结合中药调周方药,疗程3个月。观察两组治疗前后性激素水平及卵巢动脉血流变化情况。结果治疗后,两组促卵泡生成素(FSH)、促黄体生成素(LH)、雌二醇(E2)水平均较治疗前明显降低(P<0.05),且治疗组低于对照组(P<0.05)。两组卵巢动脉血流阻力指数(RI)均较治疗前降低(P<0.05);两组卵巢血流收缩期峰值流速(PSV)较治疗前显著升高(P<0.05),且治疗组高于对照组(P<0.05)。结论中药调周法可显著降低DOR患者性激素水平和改善卵巢动脉血流状况。Objective To investigate the impact of herbal menstruation-regulation therapy on sex hormones and ovarian artery blood flow in patients with diminished ovarian reserve. Methods Seventy-four subjects were divided into two groups： control group in which 37 cases were treated by elimen, and treatment group in which 37 cases were treated by climen and herbal menstruation-regulation therapy, with a course of three months. The levels of sex hormones and ovarian artery blood flow were detected before and after treatment. Results After treatment, the levels of FSH, LH and E2 were decreased significantly in both groups （ P 〈 0.05 ）, with lower levels in the treatment group than in the control group （ P 〈 0.05 ）. After treatment, the resistance indexes of ovarian artery blood flow were reduced in both groups （ P 〈 0.05 ） ; the peak systolic velocity （PSV） of ovarian artery blood flow was elevated in both groups （ P 〈 0.05 ）, with higher velocity in the treatment group than in the control group （ P 〈 0.05 ）. Conclusion Herbal menstruation-regulation therapy helps reducing sex hormones and improving ovarian artery blood flow in patients with diminished ovarian reserve.

关 键 词：卵巢储备功能下降 调周法 补肾调经方 调经方 性激素 卵巢动脉血流 

分 类 号：R271.9[医药卫生—中西医结合]