某院2015年上半年万古霉素的使用情况调查与用药合理性评价  

Utilization Investigation and Rationality Evaluation of Vancomycin during the First Half Year of 2015 in A Hospital

作　　者：石彬彬[1] 焦平[1] 林阳[1] 

机构地区：[1]首都医科大学附属北京安贞医院药事部,北京100029

出　　处：《中国药房》2016年第15期2071-2073,共3页China Pharmacy

摘　　要：目的:了解万古霉素的临床使用情况,为促进该药的合理使用提供参考。方法:回顾性调查某院2015年1-6月使用万古霉素的住院患者病历180份,就其基本情况、用法用量、病原学检查情况等进行统计,并参照国内万古霉素合理应用评价标准进行用药合理性评价,对相关不适宜情况进行总结和分析。结果:180例病例的万古霉素药物利用指数(DUI)=0.88(多为老年患者);联合用药有74例(41.11%);患者微生物检验样本送检率为84.44%(152例);越级使用万古霉素有32例(17.78%);用药不适宜病例共37例(20.56%),其中溶媒使用不适宜(12例,32.43%)和联合用药不适宜(11例,29.73%)为最主要的问题类型。结论:该院万古霉素临床使用情况较好,不存在滥用现象,微生物检验样本送检率合格,但其临床使用过程中仍存在某些问题或不足,有必要进一步规范万古霉素的用药监护,更好地保证患者的用药安全。OBJECTIVE：To investigate the utilization of vancomycin in a hospital,and provide reference for the rational use of vancomycin. METHODS：Retrospective survey was conducted for the medical records of 180 inpatients using vancomycin from Jan. to Jun.,2015 in the hospital. The general information,usage and dosage and pathogenic examination were summarized,domestic vancomycin rational use evaluation criteria was conducted to evaluate the medication rationality,summarize and analyze corresponding inappropriate questions. RESULTS：The vancomycin drug utilization index（DUI）of 180 cases was 0.88（mainly elderly patients）;the microbial test sample submission rate was 84.44%（152 cases）;there were 74 cases（41.11%）about the drug combination;32 cases（17.87%）about unauthorized use;37 cases（20.56%）about inappropriate use,in which inappropriate solvent（12 cases,32.43%）and inappropriate drug combination（11 cases,29.73%）were the main types. CONCLUSIONS：The clinical application of vancomycin is good with no abusing phenomenon,and the microbial inspection rate is qualified in the hospital.But there still exists some problems or shortcomings when using vancomycin,it is necessary to further standardize the medication monitoring of vancomycin to ensure patients’ safety.

关 键 词：万古霉素 使用情况 用药合理性 评价 

分 类 号：R969.3[医药卫生—药理学]