保健食品“黄芝精”颗粒剂成型工艺研究  

Study On Molding Technology of Health Food Huang Zhi Jing Granules

作　　者：廖秀 张丽艳[1] 包江平 曹会群 高言明[1] 

机构地区：[1]贵阳中医学院,贵阳550002

出　　处：《微量元素与健康研究》2016年第3期42-43,45,共3页Studies of Trace Elements and Health

摘　　要：目的:优选出"黄芝精"颗粒的最佳制剂工艺。方法:采用单因素实验及正交实验对辅料种类、用量、润湿剂的浓度及用量进行考查,以颗粒的成型性、吸湿性、流动性及溶化时间为评价指标,采用综合评分法,筛选出制备"黄芝精"颗粒的最优辅料。结果:"黄芝精"颗粒制剂最佳辅料为糊精,其用量为干浸膏粉:糊精为1∶1,润湿剂为70%的乙醇,其用量为总固体量1/6。结论:优选出的成型工艺合理可行,所得颗粒质量较好,符合要求。Objective： To select the optimal molding technology for Huang Zhi Jing Granules. Methods： With particles of formability, hygroscopicity, liquidity, and melting time as evaluation index, using single factor experiment and orthogonal experiment to test the varieties and amount of the accessories, the concentration and dosage of wetting agent, sdeet the best optimal exeipients of ＂Huang Zhl jing＂. Result： Dextrin is the best complementary makings of Huang Zhi Jing Granule. particles preparation of the amount of dry extract powder： dextrin as 1： 1, wetting agent of 70 % ethanol, 1/6 the amount of total solid. Conclusion： Optimization of molding process reasonable, the grain quality is better, meets the requirements.

关 键 词：黄芝精 成型工艺 颗粒剂 正交实验 

分 类 号：R283[医药卫生—中药学]